perforin
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n.
穿透细胞膜蛋白质；
英英释义
Perforin
Perforin-1 is a protein that in humans is encoded by the PRF1 gene.
以上来源于:Wikipedia
双语例句
用作名词(n.)
Cytotoxic granules contain perforin and a group of serine proteases called granzymes in a proteoglycan matrix.
细胞毒性颗粒中含有包裹在蛋白多糖基质中的穿孔素和一类被称作颗粒酶的丝氨酸蛋白酶。
权威例句
Perforin Gene Defects in Familial Hemophagocytic LymphohistiocytosisFas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity.
Functional significance of the perforin/granzyme cell death pathway.
Granzyme B and Perforin Are Important for Regulatory T Cell-Mediated Suppression of Tumor Clearance
Human T Regulatory Cells Can Use the Perforin Pathway to Cause Autologous Target Cell Death
Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways
Kagi, D. et al. Fas and perforin pathways as major mechanisms of T cell-mediated cytoxicity. Science 265, 528-530
HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors.
Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice
Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mecha...
1. Asthma; Recombinant human growth hormone; Perforin; Granzyme B; Rats;
哮喘；重组人生长激素；穿孔素；颗粒酶B；大鼠；
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2. Conclusions Perforin and granzyme B are immune markers for the identification of activated cytotoxic cells, which also can be used as diagnostic markers of NK/T-cell lymphoma.
结论穿孔素和颗粒酶B是鉴定活化的细胞毒性细胞的免疫标记物，可作为NK/T细胞淋巴瘤的诊断性标记物；
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3. Conclusion Perforin and granzyme B were immunity markers for the identification of activated cytotoxic cells, which also could be used as diagnostic markers of NK/T-cell lymphoma.
结论穿孔素和颗粒酶B是鉴定活化的细胞毒性细胞的免疫标志物，可作为NK/T细胞淋巴瘤的诊断性标志物；
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4. Cytotoxic granules contain perforin and a group of serine proteases called granzymes in a proteoglycan matrix.
细胞毒性颗粒中含有包裹在蛋白多糖基质中的穿孔素和一类被称作颗粒酶的丝氨酸蛋白酶。
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5. Results In normal mice, perforin was negative and connexin 43 was located in the intercalated disks of cardiac muscle.
结果：正常小鼠心肌中未见穿孔素阳性表达，连接蛋白43在心肌闰盘中呈阳性表达。
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6. Perforin (PFP) , a kind of glycoprotein , plays a crucial role in CTL and NK mediated cytolysis.
穿孔素（PFP）是CTL和NK赖以溶解和杀伤靶细胞的一种糖蛋白。
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7. Perforin, as its name implies, is able to target cell membrane perforation of the material.
穿孔素，顾名思义，就是能够在靶细胞膜上穿孔的物质。
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8. ObjectiveTo investigate the levels of perforin and granzyme B expressions in T lymphocyte subsets in the protective immune against tuberculosis.
目的研究结核病初期T淋巴细胞亚群内穿孔素和颗粒酶B的表达水平。
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9. This review is about recent findings on the molecular biological characteristics of perforin, the mechanism of perforin-mediated apoptosis and the function of the apoptosis on anti-infective immunity.
这种由穿孔素介导的细胞凋亡机制在抗感染免疫等方面具有非常重要的作用。
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10. Objective To study the expression of perforin protein and gene in the different phases of endometrium and the role of perforin in the reproductive system.
目的探讨穿孔素蛋白及基因在不同时期子宫内膜中表达的规律，及其在生殖系统中的作用。
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11. The observations of tumor necrosis factor and perforin reveal that cell mediated cytotoxic effects play an important role in the mechanism of this disease.
通过对肿瘤坏死因子及穿孔素的观察表明，细胞介导的细胞毒性作用在DMP的发病中起重要作用。
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12. Conclusions The up-regulation of perforin and granzyme B genes in portal vein and peripherial blood are useful early diagnostic markers of acute rejection in liver transplantation.
结论门静脉和外周血中穿孔素和颗粒酶B基因表达对肝移植急性排斥均有早期诊断价值。
www.100md.com
13. Conclusions The up-regulation of perforin and granzyme B genes in portal vein and peripherial blood are useful early diagnostic markers of acute rejection in liver transplantation.
结论门静脉和外周血中穿孔素和颗粒酶B基因表达对肝移植急性排斥均有早期诊断价值。
www.100md.com
perforin
