tumorigenesis
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n.
肿瘤发生；
权威例句
A genetic model for colorectal tumorigenesis.Cyclooxygenase-2 Inhibitors in Tumorigenesis (Part I)
DNA hypermethylation in tumorigenesis: epigenetics joins genetics
APC mutations occur early during colorectal tumorigenesis.
IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer.
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis.
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis.
Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis.
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
A Syndrome of Multiorgan Hyperplasia with Features of Gigantism, Tumorigenesis, and Female Sterility in p27 Kip1 -Deficient Mice
1. This article summarizes the role of autophagy in Tumorigenesis, Metastasis and Therapy.
本文对自噬在肿瘤发生、转移与治疗中的作用进行综述。
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2. Dysregulation of cell cycle progression is believed to play an important role in the tumorigenesis .
目前普遍认为细胞周期调控异常是肿瘤发生、发展的重要机制之一。
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3. OBJECTIVE:To explore the status of mitochondrial genome length instability in different tumors and its possible role in the tumorigenesis.
目的：探讨不同肿瘤组织中线粒体基因长度不稳定状态和在肿瘤发生中可能的作用。
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4. This article reviews the advances of researching relation between DNA methylation aberrance and transcription and tumorigenesis in the last decades, especially a recent breakthrough in cancer.
文中主要综述了几十年来人们对DNA甲基化异常与基因转录及肿瘤发生之间关系的研究进展，尤其是最近的研究突破。
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5. Therefore, the detection of oncogenes and TSGs in different tumors is the basic prerequisite to understand the mechanism of tumorigenesis and to conduct gene diagnosis and gene therapy.
因此，探讨不同类型肿瘤相关癌基因和抑癌基因是认识肿瘤发生分子机理、开展基因诊断和基因治疗的基本前提。
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6. This paper focus on the role of the homeobox gene in gastrointestinal development and tumorigenesis.
此文对同源盒基因在胃肠道发育及胃肠道肿瘤发生中的作用作一综述。
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7. The defect or block of apoptosis is also an important factor that results in the tumorigenesis and developing .
因此细胞凋亡缺陷或受阻是肿瘤发生发展的一个重要因素。
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8. BACKGROUND & OBJECTIVE: Chromosomal imbalance plays an important role in tumorigenesis of lung cancer, and may be influenced by different carcinogens.
背景与目的：染色体不平衡在肺癌发生中具有重要作用，并可能受不同致癌物的影响。
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9. Tonic formulae of Chinese medicine have been applied widely in Tumor Treatment. It can treat the precancerous lesions and prevent the tumorigenesis.
补益类中药在肿瘤治疗中应用广泛，可治疗癌前期病变，预防肿瘤发生；
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10. Over-expression of NOK gene severely caused cellular transformation as well as tumorigenesis and metastasis in nude mice.
过量表达的NOK会导致细胞转化和诱发裸鼠体内的肿瘤生成和转移。
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11. As the knowledge of tumorigenesis mechanism being more profound and extensive, scientists have focused on the correlation between epithelial tumors and BMP-2.
随着对肿瘤分子机制研究的深入，近年来上皮性肿瘤与BMP-2之间的关系已成为研究的热点。
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12. Macrophage migration inhibitory factor(MIF)is a type of cytokine which can promote tumorigenesis.
巨噬细胞移动抑制因子（MIF）是一种独特的促进恶性肿瘤发生的细胞因子。
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13. Tumorigenesis is a multistep, multistage process involving multiple genes.
肿瘤发生是一个多阶段、多途径、多基因参与的过程。
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14. Over recent years research effort has been directed at the regulation of telomere because it is involved in ageing and tumorigenesis.
因端粒与衰老、肿瘤密切相关，近年来对端粒调节的研究进一步深入。
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15. Molecular biology of tumors revealed that the imbalanced cell proliferation and cell apoptosis is an important mechanism of the tumorigenesis and progression.
肿瘤分子生物学的研究揭示细胞增殖和凋亡失衡是肿瘤发生发展的重要机制。
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16. Pituitary tumor transforming gene 1 (PTTG1) is a proto-oncogene and plays roles in promoting tumorigenesis and metastasis.
垂体肿瘤转化基因1（PTTG1）具有促进肿瘤生长和转移的作用。
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17. OPN expression may be an early molecular event in the process of tumorigenesis and could be used as a biological marker to monitor the malignant process of osteosarcoma.
OPN可能是肿瘤形成过程中的早期分子事件，可作为监测肿瘤恶性进展的一个生物学标志。
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18. More and more importance is attached to the correlation between centrosome abnormity and tumorigenesis, It refers to multiple genes abnormity, mainly separated into oncogene and tumor suppressor gene.
中心体异常与肿瘤发生的相关性已越来越受到人们的重视。
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19. Paradoxically autophagy defects are associated with increased tumorigenesis but the mechanism behind this has not been determined.
自相矛盾的是，自噬缺陷与肿瘤发生的呈正相关，但这背后的机制仍没有被明确。
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20. The discovery of oncogene and tumor suppressor gene has deepened human beings understanding of the mechanisms of cell cycle and cell apoptosis as well as the mechanisms of tumorigenesis.
癌基因，肿瘤抑制基因的发现促进了对细胞周期及细胞凋亡机制的深入理解。 使人们对肿瘤发生和发展的认识也日趋深入。
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21. To prevent the tumorigenesis, progression, invasion and metastasis is the key point to decrease the recurrence rate and case fatality rate.
防止肿瘤发生、进展和侵袭转移是降低膀胱癌复发率和病死率的关键。
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22. Objective To evaluate the effects of genomic instability or genomic damage in mouse tumorigenesis.
目的探讨鼠源性肿瘤细胞系基因组不稳定程度或基因组损伤与肿瘤发生的关系。
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23. Background: Glutamine is closely related to tumorigenesis, but its mechanism in promoting the proliferation of cultured tumor cells in vitro remains unclear.
背景谷氨酰胺与肿瘤的发生密切相关，但其促体外培养肿瘤细胞增殖的机制目前尚不明确。
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24. Conclusion: The NS can inhibit NNK induced lung tumorigenesis in mice with a better dose response relationship, and the mechanism may be related to immunoregulation of selenium.
结论：NS对NNK诱发小鼠肺癌有明显防治作用，并有较好的剂量效应关系，其机理可能与硒的免疫调节作用有关。
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25. Recent evidences suggest autophagy is a double-edged sword in Tumorigenesis and Metastasis.
既往研究表明，自噬是肿瘤发生和转移过程中的双刃剑；
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26. Many studies indicated that the GSDMDC family had many important physiological functions in development, tumorigenesis and genetic disease with deafness and hair loss phenotype.
研究表明GSDMDC家族可能与组织器官发育以及肿瘤，耳聋和脱发等遗传疾病相关，因而具有重要生理功能。
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27. Many studies indicated that the GSDMDC family had many important physiological functions in development, tumorigenesis and genetic disease with deafness and hair loss phenotype.
研究表明GSDMDC家族可能与组织器官发育以及肿瘤，耳聋和脱发等遗传疾病相关，因而具有重要生理功能。
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28. Cancer stem cells are defined as rare cells in cancer tissues with indefinite potential for self-renewal that drives tumorigenesis.
摘要肿瘤干细胞是存在于肿瘤组织内数量极少的既保持干细胞自我更新能力又能够导致肿瘤发生、发展的一群细胞。
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29. Inaro H, Onada M, Inafuku N, et al. Potent preventive action of curcumin on radintion-induced initiation of mammary tumorigenesis in rats[J]. Carcinogenesis, 2000,21:1835.
李剑明,扬和平,刘松青.3种姜黄素单体抑制人内皮细胞作用的实验研究[J].重庆医学,2002,31(9):804.
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30. Objective To investigate the tumor angiogenesis in benign, borderline and malignant epithelial ovarian tumors and its relationship with the tumorigenesis.
目的探讨良性、界性和恶性上皮性卵巢肿瘤微血管生成状态及肿瘤微血管生成与卵巢肿瘤发生、展的关系。
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31. We conclude that future studies will concentrate on how p53 functions normally,how it controls cell growth and how it suppresses tumorigenesis.
预计在一段时间内，有关P53如何发挥生理功能，抑制肿瘤生成，调节细胞生长及如何参与肿瘤发生过程等研究，将是无可争议的研究热点。
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32. At the same time, the number of driver mutations was larger than previously anticipated and, interestingly, most of the genes with driver mutations were not previously thought to be involved in tumorigenesis, indicating that more cancer genes exist than just the usual suspects.
同时，驱动突变的数目大大超过先前预期的，有趣地是，大多数带有驱动突变的基因在先前被认为是没有在肿瘤发生中起作用，暗示存在更多的癌症基因，远不止一般认为的常见突变。
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tumorigenesis
