methotrexate
n.
甲氨蝶呤，氨甲蝶呤，氨甲叶酸（一种抗肿瘤药）；
英英释义
methotrexate[ ,meθə'trekseit ]
n.toxic antimetabolite that limits cellular reproduction by acting as an antagonist to folic acid; used to treat certain cancers and psoriasis and rheumatoid arthritis
同义词：methotrexate sodiumamethopterin
双语例句
用作名词(n.)
Methotrexate and misoprostol use is a two-step method.
甲氨蝶呤和米索前列醇使用是一个分两步走的方法。
Methotrexate or leflunomide monotherapy should be started for patients with all disease durations and for all degrees of disease activity irrespective of poor prognostic features.
来氟米特或甲氨蝶呤单药治疗被推荐用于任何病程以及任何疾病活动度的患者的初始治疗，不论患者是否具有预后不良的特征表现。
权威例句
Methotrexate for rheumatoid arthritisA comparison of methotrexate with placebo for the maintenance of remission in Crohn's disease
A comparison of etanercept and methotrexate in patients with early rheumatoid arthritis.
Methotrexate and cyclosporine compared with cyclosporine alone for prophylaxis of acute graft versus host disease after marrow trans...
Methotrexate and cyclosporine versus cyclosporine alone for prophylaxis of graft-versus-host disease in patients given HLA-identical...
Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with ...
Treatment of Active Rheumatoid Arthritis With Leflunomide Compared With Placebo and Methotrexate
Phase III study comparing methotrexate and tacrolimus (prograf, FK506) with methotrexate and cyclosporine for graft-versus-host dise...
Therapeutic effect of the combination of etanercept and methotrexate compared with each treatment alone in patients with rheumatoid ...
The efficacy and safety of rituximab in patients with active rheumatoid arthritis despite methotrexate treatment: results of a phase...
1. A medical abortion with methotrexate and misoprostol is effective over 90% of the time.
药物流产与甲氨蝶呤和米索前列醇是有效的，超过90 ％的时间。
danci.911cha.com
2. Aim:To compare the effects of the drug transporter substrates such as probenecid, methotrexate, digoxin and verapamil on renal excretion of dicycloplatin in rats.
目的：比较在大鼠中丙磺舒、甲氨蝶呤、地高辛、维拉帕米等不同药物转运蛋白底物对双环铂肾排泄的影响。
www.dictall.com
3. Objective: To observe the effect and adverse reaction of small doses Tripterygium wilfordii polyglycoside (TWP) combined with methotrexate (MT) in treating rheumatoid arthritis (RA).
目的：观察小剂量雷公藤多甙和氨甲蝶呤联合治疗类风湿性关节炎的疗效和不良反应。
dict.cnki.net
4. Our conclusion is that psoriatic arthritis patients seem to benefit more from TNF-blocking agents than methotrexate when treated in daily clinical practice.
我们的结论是“与甲氨蝶呤相比，银屑病性关节炎的每日治疗中，使用肿瘤坏死因子有更多的收益。
news.dxy.cn
5. The patient was treated with methotrexate and then admitted for intravenous methylprednisolone.
患者接受了甲氨蝶呤治疗，随后静脉用甲基强的松龙。
www.medlive.cn
6. Objective:To evaluate the efficacy the safety of tripterygium hypoglaucum combined with low dose methotrexate in the treatment of elderly onset rheumatoid arthritis(EORA).
目的：观察昆明山海棠联合较小剂量甲氨蝶呤治疗老年起病类风湿关节炎（EORA）的疗效和安全性。
dict.cnki.net
7. Objective To observe the effect of methotrexate injection through intubation by hysteroscopy.
目的观察宫腔镜插管注入氨甲蝶呤治疗输卵管妊娠的疗效。
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8. Objective:To investigate the case reports of paraplegia resulting from intrathecal methotrexate administration and to analyse the factors influencing prognosis of paraplegia.
目的：调查鞘内注射甲氨蝶呤致截瘫的病例报告，分析影响截瘫预后的因素。
www.dictall.com
9. Conclusion The sequential therapy with methotrexate and mifepristone is an effective and safe method for the treatment to ectopic pregnancy with fetal cardiac activity.
结论序贯应用甲氨蝶呤与米非司酮保守治疗有胎心宫外孕是一种安全有效的方法。
dict.cnki.net
10. OBJECTIVE To study the clinical significance of monitoring the serum methotrexate concentration (MTX) after administration with high dose MTX.
目的：探讨大剂量氨甲蝶呤（MTX）用药后血药浓度监测的临床意义。
dict.cnki.net
11. Objective To discuss the practicability of high-dose methotrexate(HD-MTX) in treatment of acute lymphoblastic leukemia(ALL) in children in basic-level hospitals.
目的探讨大剂量甲氨蝶呤（HD-MTX）治疗急性淋巴细胞白血病（ALL）在基层医院的可行性。
dict.cnki.net
12. Oral mucositis is one of the common and serious complications caused by high-dose methotrexate.
口腔黏膜炎是大剂量甲氨蝶呤化疗后常见而严重的并发症之一。
www.chemyq.com
13. Objective To analyze the reproductive prognosis after treatment of tubal pregnancy with the systemic methotrexate (MTX).
目的总结甲氨蝶呤（MTX）治疗输卵管妊娠后的生殖状态。
http://dict.cnki.net
14. This is important, as people prescribed methotrexate are often advised to limit their alcohol intake to avoid possible liver problems.
这点很重要，因为根据规定，甲氨蝶呤服用过程中要限制酒精的摄入以避免可能引起的肝脏损伤。
article.yeeyan.org
15. Objectives: To observe the apoptosis effect of combination therapy with chlormethine and methotrexate on lymphocyte cells taken from rheumatoid arthritis patiences in vitro.
目的：体外观察甲氨蝶呤与烷化剂联合应用对类风湿关节炎患者淋巴细胞凋亡的作用，为临床治疗提供基础医学依据。
danci.911cha.com
16. Objective It is to observe the curative effect and safety of total glucosides of paeony(TGP) combined with low dosage methotrexate on elderly onset rheumatoid arthritis(EORA).
目的观察白芍总苷联合较小剂量甲氨蝶呤治疗老年起病类风湿关节炎（EORA）的疗效和安全性。
dict.cnki.net
17. Conclusion: The dissolution method may be used to assess the drug delivery in vitro of methotrexate implants.
结论：所定方法可用于甲氨蝶呤植入剂的体外释放测试。
dict.cnki.net
18. Conclusion TGP combined with low dosage methotrexate is effective and safe scheme on elderly onset rheumatoid arthritis.
结论白芍总苷联合较小剂量甲氨蝶呤治疗老年起病类风湿关节炎为有效、安全方案。
dict.cnki.net
19. Methotrexate or leflunomide monotherapy should be started for patients with all disease durations and for all degrees of disease activity irrespective of poor prognostic features.
来氟米特或甲氨蝶呤单药治疗被推荐用于任何病程以及任何疾病活动度的患者的初始治疗，不论患者是否具有预后不良的特征表现。
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20. Objective: To determine by IR whether the high-temperature fusion makes an impact on methotrexate structure.
前言：目的：观测甲氨蝶呤植入剂的高温融熔生产工艺对药物结构的影响。
www.chemyq.com
21. Objective To discuss the therapeutic effect of prednisone plus methotrexate(MTX) on polymyositis(PM) and dermatomyositis(DM).
目的探讨泼尼松联合甲氨蝶呤治疗多发性肌炎（PM）及皮肌炎（DM）的临床疗效。
dict.cnki.net
22. Objective:To establish the in vitro release method of the sustained-release implant of methotrexate.
目的：建立甲氨蝶呤缓释植入剂体外释放方法。
dict.cnki.net
23. Objective:To synthetize methotrexate-bisphosphonates conjugate by adaptation of directed couple method, and to identify its structure, bone target tropism and the effect of drug on osteoblast.
目的：应用无桥直接偶联模式合成靶向抗骨肿瘤偶联物甲氨蝶呤-偕二磷酸，并对其进行结构鉴定，了解其体外骨靶向性及对人成骨细胞毒性的影响。
www.dictall.com
24. Objective:To synthetize methotrexate-bisphosphonates conjugate by adaptation of directed couple method, and to identify its structure, bone target tropism and the effect of drug on osteoblast.
目的：应用无桥直接偶联模式合成靶向抗骨肿瘤偶联物甲氨蝶呤-偕二磷酸，并对其进行结构鉴定，了解其体外骨靶向性及对人成骨细胞毒性的影响。
www.dictall.com
25. FDA approves methotrexate, an anti-metabolite derived from folic acid, and6- mercaptopurine as anti-cancer drugs.
FDA批准叶酸衍化的抗代谢药甲氨蝶呤和6-巯基嘌呤作为抗癌药物.
-- 来源 -- jpkc.fimmu.com
26. Nursing Care in the Treatment of Ectopic Pregnancy by Methotrexate plus Chinese Medicinal Herb
甲氨蝶呤配合中药治疗异位妊娠的护理
-- 来源 -- 网友提供
27. Nursing about using methotrexate to cure moderate and severe psoriasis
甲氨喋呤治疗中重度银屑病的观察及护理
-- 来源 -- 网友提供
28. Nursing coordination of intra-ovidu-cal perfusion of Methotrexate to treat patients with tubal pregnancy via hysteroscope
宫腔镜下输卵管妊娠甲氨蝶呤灌注术的护理配合
-- 来源 -- 网友提供
29. A67- year-old man was switched from methotrexate therapy to leflunomide, at which time he had no rheumatoid nodules.
例67岁男性的甲氨喋呤治疗改变为来氟米特治疗，那时他没有类风湿结节。
-- 来源 -- doctorcai.net
30. According to the new report entitled Treatment Algorithms in Rheumatoid Arthritis, this limited penetration is due primarily to payer restrictions on reimbursement; patients must often fail therapy on methotrexate before the high cost of biologics will be reimbursed by health care plans.
根据这一名为类风湿性关节炎的治疗方法的报告，生物制剂受到限制主要是因为支付人偿付受限；通常病人必须在接受氨甲蝶呤治疗失败后，费用很高的生物制剂才被医疗保险计划偿付。
-- 来源 -- 网友提供
methotrexate
