verapamil
n.
戊脉安，异搏定（一种冠状动脉扩张药）；
英英释义
verapamil[ ,virə'pæmil ]
n.a drug (trade names Calan and Isoptin) used as an oral or parenteral calcium blocker in cases of hypertension or congestive heart failure or angina or migraine
同义词：CalanIsoptin
权威例句
Verapamil and adriamycin in the treatment of drug-resistant ovarian cancer patientsPromotion by verapamil of vincristine responsiveness in tumor cell lines inherently resistant to the drug.
Comparative pharmacology of calcium antagonists: nifedipine, verapamil and diltiazem.
Mechanism of Ca2+ channel blockade by verapamil, D600, diltiazem and nitrendipine in single dialyzed heart cells
Comparison of the effects of BRL 34915 and verapamil on electrical and mechanical activity in rat portal vein
Principal results of the controlled onset verapamil investigation of cardiovascular end points (CONVINCE) trial ☆
Mechanism of calcium channel blockade by verapamil, D600, diltiazem and nitrendipine in single dialysed heart cells.
Usefulness of verapamil for congestive heart failure associated with abnormal left ventricular diastolic filling and normal left ven...
Electrophysiology and pharmacology of cardiac arrhythmias. VI. Cardiac effects of verapamil
Mechanism of calcium channel blockade by verapamil, D600, diltiazem and nitrendipine in single dialyzed heart cells. Nature302, 790-...
1. Neither sodium valproate nor Verapamil showed any effect on action potential amplitude, overshoot, resting potential and phase O upstroke velocity.
丙戊酸钠和异搏定对动作电位幅度、超射值、静息电位、O期最大除极速度均无明显影响。
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2. Objective To observe the influence of verapamil injection on efficiency of peritoneal dialysis and make an inquiry into the mechanism by animal experiment.
目的动物实验观察异搏定注射液对腹膜透析效能的影响，并初步探讨其作用机理。
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3. Experiments on the isolated atrium and perfused heart of rats showed that pyquiton (Praziquantel) had positive inotropic effect which can be antagonized by Propranolol and Verapamil.
吡喹酮能增强大白鼠离体心房和灌流心脏的心肌收缩力，与异搏定和心得安有一定程度的拮抗作用。
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4. Yuanhua dose dependently increased the resting tension and the mean contractile amplitude of isolated bladder detrusor muscle strips in guinea pigs. The effect was blacked by verapamil partly.
芫花可剂量依赖性增高豚鼠膀胱逼尿肌肌条的张力，增大膀胱逼尿肌肌条的收缩波平均振幅。异搏定可部分阻断芫花增高膀胱肌条张力的作用。
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5. It was discovered that survival fractions of the synchronized cells treated with a calcium antagonist verapamil were similar with those controlled in colony forming tests.
经药物处理后进行细胞集落形成实验，发现钙拮抗刺异博定对各时相细胞集落形成率影响很小。
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6. OBJECTIVE:To study the pharmacokinetics and pharmacodynamics of verapamil in patients with hypertension.
目的：研究维拉帕米在高血压患者的药代动力学及药效学。
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7. Method Three drugs:Atropine, Nifedipine and Verapamil hydrochloride were taken by different approach to treat the spasm after bladder operation.
方法采用阿托品、心痛定和异搏定三种药物经不同的途径给药治疗膀胱术后痉挛。
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8. CONCLUSION: Verapamil can enhance the analgesic action of Asarum water decoction.
结论：维拉帕米可增强细辛水煎剂的镇痛作用。
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9. We observed the cardiac structure and function on 30 cases of normal peoples, 30 cases with hypertension and them after using Isoptin SR (verapamil SR) for 3 months.
本文通过对30例正常人、30例高血压病人及该30例病人服缓释异搏定后三个月的心脏结构及功能分析。
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10. Verapamil and erythromycin could reverse the MDR of leukemic cells.
异搏定和红霉素对白血病细胞MDR有逆转作用。
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11. The cause of death was concluded to be severe hypotension, bradycardia and cardiac failure due to combined intoxication with verapamil, metoprolol and digoxin.
死亡原因是维拉帕米、美多心安和地高辛联合中毒引起的严重低血压、心动过缓和心脏衰竭。
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12. Verapamil can attenuate the shortening effect of acute atrial dilation on AERP.
维拉帕米可以减弱急性心房扩大对AERP的缩短作用。
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13. These results showed that Verapamil can reduce incidence of ascites, prevent right ventricular hypertrophy, and maintain function of right ventricle effectively.
结果表明，维拉帕米可显著降低肉鸡腹水和右心肥大的发生，能有效维护右心功能。
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14. We concluded that diabetes mellitus reduces the antiarrhythmic effects of flecainide , E-4031, and verapamil.
我们推断糖尿病弱氟卡胺、E-4031和维拉帕米的心律失常作用。
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15. Aim:To compare the effects of the drug transporter substrates such as probenecid, methotrexate, digoxin and verapamil on renal excretion of dicycloplatin in rats.
目的：比较在大鼠中丙磺舒、甲氨蝶呤、地高辛、维拉帕米等不同药物转运蛋白底物对双环铂肾排泄的影响。
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16. Verapamil can attenuate the increasing effect of acute atrial dilation on the vulnerability to AF.
维拉帕米可以减弱急性心房扩大对房颤易感性的升高作用。
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17. We topically applied verapamil cream on the ears of guinea pigs to observe its effect.
将维拉帕米霜外涂于豚鼠耳部，观察其对豚鼠表皮的影响。
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18. Objective To evaluate the influence of verapamil on gingival fibroblast migration.
目的评价维拉帕米对牙龈成纤维细胞移出的影响。
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19. OBJECTIVE: To observe analgesic action of composition Asarum decoction made up of Asarum water decoction and verapamil by the experiment in mice.
目的：观察细辛水煎剂伍用维拉帕米配制成复方细辛水煎剂的镇痛作用，为其临床应用提供理论依据。
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20. Objective:To observe the security and efficiency of Wenxin granule and verapamil on supper ventricular premature beats.
目的：对比观察稳心颗粒与维拉帕米对室上性期前收缩的疗效及安全性。
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21. Objective: To explore the synergistic role and mechanism of verapamil in photodynamic therapy of colonic neoplasm.
目的：探讨维拉帕米在光动力学治疗结肠癌中增效作用及机制。
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22. Aim: To explore the appropriate dose of the verapamil and propranolol in kalium cardiaplegia(KVP) by observation of the effect on the function of ischemic immature rat heart and compared with ST.
目的：观察含不同剂量维拉帕米和普奈洛尔的钾停搏液对未成年缺血心脏保护效应并与高钾停搏液比较，探讨适宜剂量。
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23. The enantiomeric separation of chiral drugs mexiletine and verapamil was investigated using cyclodextrins added buffers at acidic conditions in capillary zone electrophoresis.
应用环糊精-毛细管区带电泳体系对手性药物盐酸美西律和盐酸异博定的对映体分离进行了研究。
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24. AIM: To investigate the protective effect of verapamil on lipopolysaccharide-induced pancreatic acini damage and its mechanism.
目的：研究维拉帕米对脂多糖导致的大鼠胰腺腺泡细胞损伤的拮抗作用及其机制。
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25. Atropine, verapamil and hexamethonium partly blocked the increased action of rhubarb on the isolated strips of gastric antrum in guinea pigs.
阿托品、维拉帕米和六烃季胺部分阻断大黄对豚鼠胃窦环行肌条的兴奋作用。
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26. Objective:To observe the inhibitory effect of scopolamine and verapamil on the abstinence syndrome in heroin-dependent rats.
目的：观察东莨菪碱和维拉帕米对海洛因依赖大鼠戒断症状的影响。
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27. CONCLUSION:The verapamil concentration in plasma was not fully parallel with the hypotensive effect.
结论：维拉帕米血药浓度与降血压效应呈不完全平行关系。
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28. Objective:To compare the efficacy and safety of dilacor and verapamil in the treatment of essential hypertension.
目的：比较地尔硫缓释剂和缓释维拉帕米治疗原发性轻、中度高血压的疗效和安全性。
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29. Objective:To compare the efficacy and safety of dilacor and verapamil in the treatment of essential hypertension.
目的：比较地尔硫缓释剂和缓释维拉帕米治疗原发性轻、中度高血压的疗效和安全性。
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30. · RESUlTS: Verapamil can induce apoptosis of hRPE. Apoptosis features were observed by AO staining with fluorescence microscope: nucleolus fluorescence was kelly.
一定浓度Ver可诱导hRPE细胞凋亡,荧光显微镜及电镜观察hRPE细胞具有早期凋亡特征:核荧光呈黄绿色,电镜下核染色质浓染、边集。
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31. Verapamil Hydrochloride
盐酸维拉帕米
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32. The results showed that verapamil increased urine flow and creatinine clearance rate( Ccr), decreased BUN and protected against ARF.
结果表明,异搏停能增加尿量和肌酐清除率,降低血尿素氮,具有防治急性肾功能衰竭的作用。
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33. Method: Using the method of agar dilution to measure the MIC of 86 strains clinically isolated Pseudomons aeruginosa with four kinds of quinolone individually and combined with reserpine and verapamil.
方法 :通过琼脂二倍稀释法检测 86株铜绿假单胞菌对四种喹诺酮类药物与利舍平及维拉帕米联用前后的MIC值及 86株铜绿假单胞菌对其它常用抗生素的 MIC值 ;
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34. The mechanisms of verapamil protection against ARF are: verapamil increased renal blood flow and GFR, improved renal cortical blood circulation, etc.
其机理与增加肾血流量、善肾皮质缺血区域的血液循环等因素有关。
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35. Changes in renal function and blood flow redistribution after injection of verapamil in rabbits with glycerol-induced acute renal failure( ARF) were studied with radioactive biologic microsphere technique.
实验观察了在家兔甘油性急性肾功能衰竭时异搏停对肾脏功能及血流的影响。
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36. A71- year-old man was admitted for coronary angiography because of arrhythmia and received clopidogrel( dosage not stated), aspirin, verapamil and statins.
例71岁男性因心律不齐，接受氯吡格雷(剂量不详)、斯匹林、搏定和他汀类药物治疗，为进行冠状动脉造影术入院。
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37. The cause of death was concluded to be severe hypotension, bradycardia and cardiac failure due to combined intoxication with verapamil, metoprolol and digoxin.
死亡原因是维拉帕米、多心安和地高辛联合中毒引起的严重低血压、动过缓和心脏衰竭。
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38. We speculate that the fatal effect was primarily due to the overdose of verapamil.
我们推测，死亡原因可能是最初使用了超量的维拉帕米。
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39. Methods Ligate rat left common carotid artery 1 h, then reperfuse, inject verapamil intraperitoneally at the same time, exam retina ERG in 1 h, 6 h, 12 h, 24 h, 48 h, 72 h.
方法 :通过结扎大鼠左颈总动脉 1h ,然后再灌注 ,同时向腹腔注射异博定 ,检测 1h ,6h ,12h ,2 4h ,48h ,72h视网膜ERG的变化。
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verapamil
