integrase
n.
整合酶；
英英释义
Integrase
Retroviral integrase (IN) is an enzyme produced by a retrovirus (such as HIV) that enables its genetic material to be integrated into the DNA of the infected cell. Retroviral INs are not to be confused with phage integrases, such as λ phage integrase (Int) (see site-specific recombination).
以上来源于:Wikipedia
双语例句
用作名词(n.)
Thus, emphasis should be laid to search for new integrase inhibitors with high activities to provide a new way of treating AIDS.
应着眼于寻找高活性的整合酶抑制剂，为治疗艾滋病提供新的途径。
权威例句
Integrase inhibitors to treat HIV/AIDS.A phage integrase directs efficient site-specific integration in human cells.
Integrase inhibitors and cellular immunity suppress retroviral replication in rhesus macaques.
Integrase inhibitors and cellular immunity suppress retroviral replication in rhesus macaques.
HIV-1 Integrase Forms Stable Tetramers and Associates with LEDGF/p75 Protein in Human Cells
Binding and stimulation of HIV-1 integrase by a human homolog of yeast transcription factor SNF5
Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: a platform for antiviral drug design
Construction of transgenic Drosophila by using the site-specific integrase from phage phiC31.
Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases
Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery
1. Objective: To rationally design new inhibitors of HIV-1 integrase.
目的：合理设计新的HIV-1整合酶抑制剂。
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2. Integrase is one of the three enzymes of the irus that is required for iral replication.
整合酶是病毒复制所需要的三种酶之一。
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3. Two are "integrase inhibitors" that block the HIV genetic material from attaching to the host cell's DNA.
其中两种药物是“整合?抑制剂”，它可以阻止艾滋病病毒的遗传物质附加到宿主细胞的DNA中。
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4. Because of the special function of HIV-1 integrase, it has become one of focuses of anti-AIDS drug design.
由于HIV - 1整合酶的特殊功能，它已成为抗艾滋病药物设计工作的焦点之一。
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5. HIV-1 integrase (in) integrates viral DNA into host cells through two steps metal ions-dependent reactions.
HIV - 1整合酶(IN)通过依赖金属离子的两步反应将病毒DNA整合入宿主细胞中。
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6. Aim To synthesize a series of new caffeic acid derivatives and test their HIV-1 integrase inhibitory activities.
目的合成新型咖啡酸衍生物并测定其抑制HIV 1整合酶活性。
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7. Integrase inhibitors 2007 integrase inhibitors interfere with the integrase enzyme, which HIV needs to insert its genetic material into human cells.
整合酶抑制剂；首次获准：2007年；抗病毒方式：整合酶抑制剂干预了整合酶酵素，艾滋病病毒正是通过整合酶酵素将自己的遗传物质传到人类细胞。
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8. Results:After being identified by PCR, restriction enzyme digestion and sequencing, the adeno-integrase hybrid system was successfully constructed.
结果：经PCR，酶切及测序方法鉴定，该腺病毒-整合酶嵌合系统构建成功。
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9. Results Positive rates of class 1 integrase gene was 61.4%(113/184) in clinical isolates, class 2 integrase gene 4.3%(8/184) and class 3 integrase gene zero.
结果1类整合酶基因总阳性率为61.4%（113/184），2类整合酶基因总阳性率为4.3%（8/184），未检出3类整合酶基因阳性菌株。
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10. The integrase inhibitor MK-0518 worked as effectively as the best treatment available for individuals who have not previously received antiretroviral therapy.
整合酶抑制剂MK- 0518对以前没接受过抗病毒治疗病人，疗效就像目前最好的药物组合一样有效。
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11. Inhibition experiment was performed as integrase activity assay expect that increasing concentrations of synthetic peptides were preincubated with the integrase.
实验方法与整合酶活性检测相似，只是整合酶需要和合成的多肽先进行预反应。
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12. By producing a more accurate model of integrase, the research allows further searches for new drug molecules that will inhibit the mutant drug resistant forms of this enzyme, as well.
通过构建更精确的整合酶模型，这技术使未来未来搜寻新的药物分子成为可能，这些新药物分子将能通过稳定病毒蛋白酶的结构来抑制突变病毒的抗药性。
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13. Terphenyllin has not been extensively studied but has been reported to exhibit anti-oxidative activity, acts as a plant growth inhibitor and shows weak activity against HIV integrase.
三联苯曲菌素还没有被广泛的研究但已报道显示其有抗氧化的活性，做为一种植物生长抑制剂，也显示了弱的抗HIV整合酶的活性。
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14. The application value of each representative system was evaluated to provide some guidance for the platform established for the drug design and screening of HIV-1 integrase inhibitors.
给出了各个代表性体系的应用价值。旨在对HIV - 1整合酶抑制剂药物设计及筛选平台的建立提供一定的参考。
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15. The application value of each representative system was evaluated to provide some guidance for the platform established for the drug design and screening of HIV-1 integrase inhibitors.
给出了各个代表性体系的应用价值。旨在对HIV - 1整合酶抑制剂药物设计及筛选平台的建立提供一定的参考。
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integrase
