topiramate
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释义
托吡酯；
权威例句
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PHARMACEUTICAL CO-CRYSTAL COMPOSITIONS OF DRUGS SUCH AS CARBAMAZEPINE, CELECOXIB, OLANZAPINE, ITRACONAZOLE, TOPIRAMATE, MODAFINIL, 5...
1. You should tell your healthcare professional right away if you become pregnant while taking topiramate.
如果使用托吡酯时怀孕了，您需要立即告诉您的医疗保健专业人员。
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2. Women should talk to their healthcare professionals about the best kind of birth control to use while taking topiramate.
女性需要向医疗保健专业人员咨询使用托吡酯期间应当采用的最佳避孕方法。
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3. You should inform women of childbearing age of the increased risk for oral clefts when topiramate is used in the first trimester of pregnancy.
您需要告知育龄女性如果在怀孕的第一孕期使用托吡酯，会增加婴儿发生唇腭裂的风险。
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4. For example, 43% of topiramate patients experienced central and peripheral nervous system disorders, compared to 21% of placebo patients. For psychiatric disorders, the figures were 33% and 11%.
例如，43%的托吡酯组患者出现中枢和外周神经系统失调症状，与之相比，安慰剂组仅为21%；而精神方面症状，两组分别为33%和11%。
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5. The aim of this study was to measure differences in occipital cortex excitability in migraineurs before and after administration of topiramate.
研究目的是测量应用托吡酯前后偏头痛患者枕叶皮质兴奋性的变化。
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6. You and your healthcare provider should decide if you will continue to take topiramate while you are pregnant.
他（们）会和你讨论确定在您怀孕期间是否应继续使用托吡酯。
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7. You should talk to your healthcare professional about the best way to feed your baby if you take topiramate.
如果你在使用托吡酯，您需要向医疗保健专业人员咨询哺育您孩子的最佳方法。
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8. However, the researchers note that there were substantially more CNS and psychiatric adverse events in patients treated with topiramate. Such findings were similar to those previously reported.
但是，研究人员注意到，接受托吡酯治疗的患者出现明显较多的中枢神经系统和精神方面不良事件，这与以前的报道相类似。
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9. The main adverse reactions of topiramate group were gastrointestinal symptoms as same as the carbamazepine group except loss of body weight.
托吡酯组常见的不良反应是胃肠症状，除体重下降外，与卡马西平组无显著差异。
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10. Before you start topiramate, you should tell your healthcare professional if you are pregnant or are planning to become pregnant. Healthcare professionals may discuss other treatment options with you.
如果您是孕妇或者计划怀孕，在您开始使用托吡酯之前您需要将这些信息告诉您的医疗保健专业人员。他（们）会和你讨论是否采用其它的治疗方法。
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11. Topiramate also significantly reduced blood pressure and urinary albumin excretion.
托吡酯还显著降低血压和尿蛋白排泄。
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12. It has since been demonstrated that topiramate can act both as an insulin secretagogue and sensitiser in T2DM animal models.
这说明在T2DM动物模型中，托吡酯同时有胰岛素促泌剂和胰岛素增敏剂作用。
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13. Objective To study the influence of valproate sodium(VPA)on neuroprotective effects of topiramate(TPM).
目的研究丙戊酸钠（VPA）对托吡酯（TPM）神经保护作用的影响。
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14. Conclusions:Topiramate might decrease the seizure duration of the amygdaloid kindled rats, as well as the ADD of the amygdaloid and the cortex, and increase the ADT of the amygdaloid.
结论：托吡酯可明显缩短杏仁核点燃大鼠癫癎发作时间，缩短杏仁核及皮层后放电持续时间，升高杏仁核后放电阈值。
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15. Objective To observe the effect and safety of Topiramate in the long-term treatment of various pediatric epilepsy.
目的：观察托吡酯长期治疗儿童各型癫痫的疗效和安全性。
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16. The study involved a new combination of two existing drugs: phentermine, a prescription short-term weight-loss drug, and topiramate, an anti-epilepsy medication that also leads to weight loss.
此项研究应用了两种现存药物的新组合：芬特明，一种短效处方减肥药。托吡酯，一种有减肥作用的抗癫痫药。
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17. Aim: To explore the effects of topiramate (TPM) on the expression of interleukin-6 (IL-6) in the hippocampus of pentylenetetrazol(PTZ) kindling rats.
目的：探讨戊四氮（PTZ）点燃大鼠海马结构白细胞介素-6（IL-6）表达的特征及托吡酯（TPM）对其表达的影响。
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18. Questions about the neurologic and psychiatric effects of topiramate and the cardiovascular impact of phentermine are expected.
托吡酯的中枢神经系统的副作用和芬他命的胃肠道反应得到关注。
article.yeeyan.org
19. Objective:To observe the clinical efficacy and adverse reaction(AR)of topiramate(TPM)in treatment of epilepsy, and to explore the optimal mode of administration.
目的：观察托吡酯治疗癫痫的临床疗效及不良反应，探讨治疗的理想给药模式。
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20. Conclusion:Topiramate may be used as a first line drug for childhood epilepsy for its effectiveness and safety.
结论：托吡酯对儿童多种类型癫疒间有良好疗效，安全性高，可以作为儿童癫疒间一线治疗药物。
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21. Conclusions Topiramate is effective in the treatment of splitting headache.
结论托吡酯治疗偏头痛疗效确切，值得临床推广。
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22. If the decision is made to use topiramate in women of childbearing age, effective birth control should be used.
如果确定育龄女性需要使用托吡酯，必须采取有效的避孕措施。
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23. Inform women of childbearing age of the increased risk for having a baby with an oral cleft if they become pregnant while using topiramate.
需要告知育龄女性使用托吡酯时如果怀孕，他们孩子发生唇腭裂的风险将增加。
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24. Objective To assess the efficacy and safety of topiramate (TPM) as add on therapy in patients with intractable epilepsy (IE).
目的观察添加托吡酯（TPM）对难治性癫痫（IE）的临床效果与安全性。
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25. Objective:To observe the prophylactic effect and side effects of topiramate(TPM)with monotherapy in febrile seizure in rats.
目的：观察托吡酯预防动物热性惊厥发作的疗效与毒副反应。
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26. Topiramate passes into breast milk, but its effects on developing babies remain unknown.
托吡酯可以通过乳汁分泌，但是他们对婴儿发育的影响尚不清楚。
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27. Aim:To investigate whether changes of insulin and leptin levels play a role in the weight loss associated with topiramate and the weight gain associated with valproate acid in epileptic patients.
目的：研究服用托吡酯、丙戊酸的癫病人的体重变化是否与胰岛素和瘦素水平的变化有关。
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28. Aim:To investigate whether changes of insulin and leptin levels play a role in the weight loss associated with topiramate and the weight gain associated with valproate acid in epileptic patients.
目的：研究服用托吡酯、丙戊酸的癫病人的体重变化是否与胰岛素和瘦素水平的变化有关。
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topiramate
