topoisomerase
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释义
局部异构酶；
英英释义
Topoisomerase
Topoisomerases (type I: , type II: ) are enzymes that regulate the overwinding or underwinding of DNA. The winding problem of DNA arises due to the intertwined nature of its double helical structure.
以上来源于:Wikipedia
双语例句
用作名词(n.)
The raw materials plant resources of topoisomerase inhibitors were investigated, which provided basic data for the exploitation and utilization of these resources.
对昆奇山拓扑异构酶抑制刑的植物资源进行了调查，为该资源的开发利用提供基础资料。
权威例句
DNA gyrase, topoisomerase IV, and the 4-quinolones.Topoisomerase II levels during granulocytic maturation in vitro and in vivo
Re: Topoisomerase II alpha and responsiveness of breast cancer to adjuvant chemotherapy.
Camptothecin induces protein-linked DNA breaks via DNA topoisomerase
Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I.
Alteration of Topoisomerase II–Alpha Gene in Human Breast Cancer: Association With Responsiveness to Anthracycline-Based Chemotherapy
Effect of adding the topoisomerase I poison 7-ethyl-10-hydroxycamptothecin (SN-38) to 5-fluorouracil and folinic acid in HCT-8 cells...
Intercalative antitumor drugs interfere with the breakage-reunion reaction of mammalian DNA topoisomerase II.
Resistance of human leukemic and normal lymphocytes to drug-induced DNA cleavage and low levels of DNA topoisomerase II
Chromosomal loop anchorage of the kappa immunoglobulin gene occurs next to the enhancer in a region containing topoisomerase II sites
1. Topoisomerase I then ligates the PCR product in the correct orientation.
然后拓扑异构酶I将PCR产物按照正确的方向连接。
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2. Conclusion: The mouse TFAR19 sequence is highly homologous with human TFAR19 and may have functional relationship with DNA topoisomerase I.
结论：小鼠TFAR19是与人TFAR19高度同源的新基因，与DNA拓扑异构酶I可能有功能相关性。
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3. In addition, the paper reviewed screening methods for differentiation inducers, DNA topoisomerase inhibitors, antimicrotubule drugs and biological response modifiers.
还对分化诱导剂、拓扑异构酶抑制剂、抗微管药和生物反应调节剂的筛选方法进行了评述。
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4. Purpose To investigate the relationship between DNA topoisomerase and cell proliferation, apoptosis in ovarian carcinomas.
目的：探讨DNA拓扑异构酶在卵巢浆液性、黏液性囊腺癌中的表达及与细胞增殖、凋亡的关系。
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5. The resistance to quinolones in clinical isolates of Pseudomonas aeruginosa is due to the mutations of two types of topoisomerase plus efflux pump.
结论铜绿假单胞菌的耐药性日趋严重，两类拓扑异构酶基因突变和泵出机制形成了铜绿假单胞菌对喹诺铜类药物耐药的主要机制。
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6. AIM: To find natural DNA topoisomerase I inhibitors from Camptotheca acuminata Decne.
目的以生物活性为向导在喜树中寻找天然的DNA拓扑异构酶I抑制剂。
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7. The specific activity of topoisomerase I was higher in proliferating tissues and much higher in malignant tissues than that in differentiated tissues.
发现增殖组织全细胞抽提液中酶比活高于正常分化组织，而且在异常增殖组织中酶比活的增高更为显著。
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8. AIM:To study the effects of shikonin on the catalytic activity of DNA topoisomerase I and apoptosis of K562 leukemia cells.
目的：研究紫草素对DNA拓扑异构酶I催化活性和K5 6 2白血病细胞凋亡的影响。
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9. New cytotoxic drugs, such as taxanes and topoisomerase inhibitor etc, and new regimens are focus researches for medical treatment.
新的细胞毒药物如紫杉醇类、拓扑异构酶抑制剂及新联合方案是研究的热点；
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10. Mutation of type II topoisomerase gene;
拓扑异构酶II基因突变；
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11. Mutation of type II topoisomerase gene;
拓扑异构酶II基因突变；
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12. DNA topoisomerase
ＤＮＡ拓扑异构酶
-- 来源 -- 英汉 - 翻译参考[网络]
13. The effect of EB virus bhrfl gene expressing on the topoisomerase Ⅰ expression in nasopharyngeal carci noma cell line
Epstein-Barr病毒bhrfl表达对鼻咽癌细胞株CNE2拓扑异构酶Ⅰ表达的影响
-- 来源 -- 网友提供
topoisomerase
