Sirolimus
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释义
[医]西罗莫司；
双语例句
用作名词(n.)
Sirolimus is an immunosuppressive drug, while paclitaxel is an anti-cancer drug.
西罗莫司是一种免疫抑制药物，而紫杉醇是一种抗肿瘤药物。
This study supports the conduct of larger randomized trials inestigating sirolimus after transplantation for HCC.
该研究支持进行大型随机试验调查在肝细胞癌肝移植后西罗莫司的作用。
权威例句
Safety and Efficacy of Sirolimus- and Paclitaxel-Eluting Coronary Stents — NEJMSirolimus-Eluting vs Uncoated Stents for Prevention of Restenosis in Small Coronary Arteries: A Randomized Trial
Safety of coronary sirolimus-eluting stents in daily clinical practice: one-year follow-up of the e-Cypher registry.
Tirofiban and sirolimus-eluting stent vs abciximab and bare-metal stent for acute myocardial infarction: a randomized trial.
Sirolimus-Eluting Stents Remain Superior to Bare-Metal Stents at Two Years : Medium-Term Results From the Rapamycin-Eluting Stent Ev...
Sirolimus-eluting stents for treatment of patients with long atherosclerotic lesions in small coronary arteries: double-blind, rando...
Unrestricted utilization of sirolimus-eluting stents compared with conventional bare stent implantation in the "real world": the Rap...
Lack of neointimal proliferation after implantation of sirolimus-coated stents in human coronary arteries: a quantitative coronary a...
Early and late coronary stent thrombosis of sirolimus-eluting and paclitaxel-eluting stents in routine clinical practice: data from ...
Stent underexpansion and residual reference segment stenosis are related to stent thrombosis after sirolimus-eluting stent implantat...
1. AIM: To study the therapeutic window of sirolimus concentration in Chinese kidney transplantation recipient.
目的：探讨西罗莫司应用于国内肾移植受者的治疗窗范围。
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2. Ascites is an adverse effect with an incidence between 3% and 20%, but no relation between sirolimus and chylous ascites was previously established.
腹水作为一种不良反应其发生率为3%至20%，但是先前并没有认为西罗莫司和乳糜性腹水相关。
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3. BACKGROUND: Animal and limited human studies have raised concerns as to the safety of in utero exposure to mycophenolate mofetil (MMF) and sirolimus (SRL) in transplant recipients.
背景：动物研究和有限的人体研究已经增加了对移植受体子宫内骁悉（MMF）或西罗莫司（SRL）暴露的安全性关切。
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4. Objective This study evaluated the outcomes of sirolimus-eluting stents in patients with coronary artery disease and type 2 diabetes.
目的评估冠心病合并2型糖尿病患者冠状动脉内植入雷帕霉素洗脱支架的临床疗效。
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5. In all 4 patients, sirolimus-induced pneumonitis resolved following cessation of therapy but took weeks to months for complete recovery.
全部4名患者的西罗莫司诱导性肺炎都在治疗结束得到消散，但数周至数月后才完全康复。
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6. Background: The long-term incidence of stent thrombosis (ST) and complications after sirolimus-eluting stents (SES) implantation is still a matter of debate.
背景：西罗莫司洗脱支架（SES）置入后长期支架血栓（ST）和并发症的发生率仍然是争论的话题。
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7. Hence, vaccination guidelines in place for CNI treated patients are likely to be appropriate for transplant recipients maintained on sirolimus.
因此，对于CNI治疗患者的疫苗接种指南很可能适合持续应用西罗莫司的移植受体。
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8. Conclusion Compared to mycophenolic acid, sirolimus and FTY720 demonstrate lower (toxicity) effect on human adult islets in vitro.
结论相对来说，在体外雷帕霉素和FTY720对成人胰岛细胞的毒性作用较小；
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9. The effect of sirolimus, a new immunosuppressant, on vaccine responses has been little studied.
西罗莫司（一种新的免疫抑制剂）对于接种疫苗应答影响的研究尚少。
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10. Sirolimus is indicated for the prophylaxis of organ rejection in patients aged 13 years or older receiving kidney transplants.
西罗莫司用于在13岁及以上接受肾移植患者中预防器官排斥反应。
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11. However, only the TYPHOON trial involving the sirolimus-eluting stent significantly reduced its primary endpoint of target vessel failure compared with an uncoated stent.
但是，只有关于西罗莫司洗脱支架的TYPHOON试验表明，与裸支架组相比显著降低了作为主要终点的靶血管障碍率。
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12. At this time, FDA has not made any changes to the professional label for sirolimus.
目前，FDA尚未对西罗莫司的专业标签信息做出任何修改。
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13. Objectives: We examined the impact of gender on outcomes of patients undergoing percutaneous coronary intervention using sirolimus-eluting stents (SES).
目的：观察性别对于经皮冠脉植入西罗莫司洗脱支架的临床获益有无显著影响。
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14. Objective: To observe the difference of cardiovascular event occurrence rate between patients implanted with sirolimus-eluting stents and paclitaxel-eluting stents.
目的：观察冠心病患者应用雷帕霉素洗脱支架与紫杉醇洗脱支架后临床不良心血管事件的发生率。
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15. Revascularization rates were similar with the sirolimus- and paclitaxel-eluting stents in the two trials, at 5.6% versus 5.3%, respectively.
再次血运重建率在西罗莫司和紫杉醇的两个临床试验类似，分别为5.6%和5.3%。
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16. We conclude that sirolimus therapy may induce RSDS in renal transplant recipients.
我们总结认为，西罗莫司疗法可能会诱导肾移植患者发生RSDS。
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17. Conclusions: Nonresponsiveness to clopidogrel is a strong independent predictor of stent thrombosis in patients receiving sirolimus- or paclitaxel-eluting stents.
结论：在植入西罗莫司或者紫杉醇药物洗脱支架患者中对氯吡格雷无效是预测支架血栓性的独立强先兆。
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18. We present a clinical report of chylous ascites in a renal transplant patient under sirolimus therapy; our investigation pointed to sirolimus as the cause.
我们报道使用西罗莫司的一例肾移植患者发生乳糜性腹水，我们的研究提示西罗莫司的使用是其产生的原因。
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19. Mortality was similar with bare-metal, sirolimus-eluting, and paclitaxel-eluting stents, but sirolimus stents were superior to the other types in terms of MI and revascularization.
裸支架，西罗莫司药物支架和紫杉醇药物支架析死亡率相似，但西罗莫司支架在心梗和血运重建方面要优于其它类型。
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20. The FDA is determining whether a labeling change for sirolimus is needed.
FDA正在酝酿是否需要修改西罗莫司的标签信息。
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21. This study supports the conduct of larger randomized trials investigating sirolimus after transplantation for HCC.
该研究建议进行更大型的随机试验来研究西罗莫司对于肝癌行肝移植患者的作用。
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22. Also known as sirolimus, rapamycin was first discovered as a product of the bacterium Streptomyces hygroscopicus, which was found in an Easter Island soil sample.
雷帕霉素也被称作西罗莫司，最初是作为吸水链霉菌制品被发现的。该细菌来自于复活节岛的土壤样本中。
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23. Of 186 liver transplant patients receiving sirolimus, 4 (2.2%) developed pneumonitis that was attributed to the drug;
在接受肝移植的186名患者中，有4名（2.2%）患者发生西罗莫司诱导性肺炎；
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24. The drug is rapamycin, also called sirolimus, and is currently used as an immunosuppressant, to help prevent rejection of a new, transplanted kidney.
这种药物是瑞帕霉素，又被称为西罗莫司，目前被用于作为一种免疫抑制剂，有助于防止新移植肾脏发生排异。
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25. Sirolimus is a kind of anti-proliferation drug, and acrylate resin is a kind of universal non-degradable biomaterial, moreover, PLGA is a kind of biodegradable medical polymer.
雷帕霉素是一种抗增生型药物，丙烯酸树脂是一种通用的非降解型医用高分子材料，而PLGA是一种常用的可降解医用高分子材料。
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26. A total of 804 patients who had successful sirolimus- or paclitaxel-eluting stent implantation were assessed for post-treatment platelet reactivity after a loading dose of 600 mg of clopidogrel.
总共804名成功植入西罗莫司或紫杉醇药物洗脱支架的病人，检查了他们在服用了600mg负荷计量的氯吡格雷之后的治疗后血小板活性。
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27. Therapeutic drug monitoring should not be the sole basis for adjusting sirolimus therapy.
治疗药物监测不应作为调整西罗莫司治疗的唯一根据。
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28. This information is in the Boxed Warning of the sirolimus label.
这一点在西罗莫司标签的黑框警告中有提示。
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29. This information is in the Boxed Warning of the sirolimus label.
这一点在西罗莫司标签的黑框警告中有提示。
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Sirolimus
