exon
推荐文章
释义
外显子；
英英释义
exon[ 'eksɔn ]
n.sequence of a gene's DNA that transcribes into protein structures
"exons are interspersed with introns"
同义词：coding DNA
权威例句
Exon recognition in vertebrate splicingJAK2 Exon 12 Mutations in Polycythemia Vera and Idiopathic Erythrocytosis
Pooled Association Tests for Rare Variants in Exon-Resequencing Studies
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
Dopamine D4 receptor (D4DR) exon III polymorphism associated with the human personality trait of Novelty Seeking.
A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene
Sequence of the intron/exon junctions of the coding region of the human androgen receptor gene and identification of a point mutatio...
Activation of the β-Catenin Gene in Primary Hepatocellular Carcinomas by Somatic Alterations Involving Exon 3
The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing.
Clinical course of patients with non-small cell lung cancer and epidermal growth factor receptor exon 19 and exon 21 mutations treat...
1. AVI is also evaluating a drug candidate AVI-5038, designed to skip exon 50, which is in preclinical development.
阿维也是衡量一个候选药物阿维-5038，旨在跳过外显子50个，处于临床前开发的。
www.jingcai.org
2. AIM:To observe the correlation of the 17 exon gene polymorphism of insulin receptor gene and the Chinese cerebral infarction and primary hypertension.
目的：观察胰岛素受体基因第17外显子基因多态性与中国人脑梗死和原发性高血压的相关性。
dict.cnki.net
3. Methods Exon 4~9 of PTEN were amplified by polymerase chain reaction (PCR) for homozygous deletions in 110 tumor samples of patients with bone and soft tissue tumors, 3 tumor cell lines.
方法应用聚合酶链反应（PCR）分析骨及软组织肿瘤患者110例肿瘤标本，3个肿瘤细胞系PTEN基因第4～9外显子有无纯合性缺失。
dict.cnki.net
4. AIM: To establish the mutant of coding calcium binding fragment of the 13th exon of human thrombospondin-1 (TSP-1) gene with polymerase chain reaction (PCR) site directed mutagenesis technology.
目的：利用聚合酶链反应定点突变技术构建人血小板反应素1基因第13外显子编码钙结合域突变体。
dict.cnki.net
5. Objective To investigate the relationship between the point mutation of ABCB4 gene exon 23 and the intrahepatic cholestasis of pregnancy (ICP).
目的：探讨ABCB4基因外显子23点突变与妊娠期肝内胆汁淤积症（ICP）发病的关系。
www.chemyq.com
6. Median survival time for patients with an EGFR exon 19 deletion in serum was also substantially higher than in those with L858R mutations (32 months vs 14 months).
血浆中EGFR外显子19删除患者的中位生存期要明显好于那些存在L858R变异患者（32个月相对14个月）。
news.dxy.cn
7. Objectives To study the feature of disease causing mutation of exon 12 of Wilson disease (WD) gene in Chinese and evaluate its value in direct gene diagnosis.
目的研究中国人肝豆状核变性（WD）基因12号外显子的突变特征，为建立直接基因诊断的方法提供理论依据。
dict.cnki.net
8. Result:①Allele B is the main variant leading to polymorphism within exon 1 of MBL gene in Hubei, the spot of mutation is located on codon 54(GGC→GAC), allele C and D were not found.
结果①B等位基因是湖北地区汉族人群MBL基因外显子1区的主要变异体，其突变位点位于54位密码子（GGC→GAC），未检出C、D变异体。
dict.cnki.net
9. Conclusion There is polymorphism at 20 exon LEPR gene in children with obesity, which may affect the lipid metabolism and the fat distribution.
结论单纯型肥胖儿童瘦素受体基因第20外显子存在基因多态性的变化，且这种变化明显影响肥胖儿童的脂质代谢及体脂分布。
dict.cnki.net
10. Objective: To screen the mutations of PS-1 gene exon 5-9, discuss the distributing of PS-1 and evaluate its effects on the pathogenesis of AD in Chinese population.
目的：筛查PS-1基因外显子5～9的突变，了解PS-1基因突变在中国人群中的分布情况及在中国人群阿尔茨海默病（AD）发病中可能产生的影响。
dict.cnki.net
11. Exon Trapping is a powerful method developed recently for isolating transcribed sequences from genomic DNA.
外显子捕获是近年发展起来的一种自基因组DNA分离表达序列的有效方法。
www.dictall.com
12. The results demonstrated that the mutation in the fourth exon and the DNA sequence in the three exons of PIT-1 gene were probably independent of dwarfism of Xiang pigs.
研究结果初步证明：PIT-1基因第四外显子中的碱基突变及这1个外显子的序列状况可能与香猪的矮小性无关。
dict.cnki.net
13. HLA DPB1 exon nucleic acid sequence was determined by direct nucleic acid sequence analysis of PCR product after purification.
产物纯化后，直接核酸序列分折确定个体的HLADPB1外显子核酸序列。
dict.cnki.net
14. Objective: The study was to survey genetic compound in exon 7 of PAH gene responsible for PKU, its characteristics and detecting method.
目的：筛查苯丙酮尿症（PKU ）患者PAH基因外显子7遗传复合体突变的特点和检测。
www.dictall.com
15. Methods:1PCR-restriction enzyme digestion and denaturing high-performance liquid chromatography(DHPLC) methods were applied to detect the deletion of the exon 7 and 8 of SMN1 gene.
方法：1、联合应用PCR限制性酶切及变性高效液相色谱（DHPLC）技术对运动神经元生存基因（SMN1）7、8号外显子进行缺失检测。
dict.cnki.net
16. Comclusion SNP site on vitamine D receptor gene exon 2 is one with high polymorphism and certain popu-lational diversity.
结论维生素D受体基因2号外显子SNP基因座具有较高的多态性，并具有一定的群体差别。
dict.cnki.net
17. Conclusion The SMNt gene exon 7 and 8 examine can be applied to SMA gene diagnosis, and the PCR- RFLP method have higher sensitivity and particularity to the SMA diagnosis.
结论检测SMN基因第7和第8号外显子缺失的方法可用于SMA的基因诊断，且PCR—RFLP技术对SMA的诊断具有较高的特异性和敏感性。
dict.cnki.net
18. Specific primers were designed for MSX1 and PAX9 respectively. Mutation analysis was performed by direct sequencing of all the coding exons and intron-exon boundaries.
分别设计MSX1、PAX9基因特异性引物，聚合酶链反应扩增全部外显子编码区和内含子-外显子剪接序列，产物纯化后直接测序。
dict.cnki.net
19. Objective To investigate insulin receptor (INSR) genotype exon 17 frequencies in women with polycystic ovary syndrome(PCOS) and to elucidate its role in the pathogenesis of PCOS.
目的探讨胰岛素受体基因外显子17与多囊卵巢综合征（PCOS）发病的关系。
dict.cnki.net
20. Conclusion: No correlation was found between glucocorticoid receptor gene in exon 2/1 codons 23 and asthma.
结论：江西籍汉族人种中糖皮质激素受体基因外显子2/1密码子23基因未发现多态性的存在。
dict.cnki.net
21. Foreign gene (double stranded DNA) is maybe integrated in different DNA strand of the same chromosome as an exon. The first generation of transgenic fish is mosaic.
外源基因（双链DNA）作为外显子可能整合在一条染色体上的不同DNA链上，转基因鱼的第一代为嵌合体。
dict.cnki.net
22. Objective To evaluate the relationship between T174M and M235T polymorphisms of angiotensinogen (AGT) gene in exon 2 and brain infarction (BI) in Chinese Han population.
目的研究血管紧张素原（AGT）基因第2号外显子T174M和M235T多态与中国汉人脑梗塞发病的关系。
dict.cnki.net
23. Conclusion Exons 2 5 of UGT1F are highly conservative, but exon 1 emerges highly polymorphic.
结论UGT1F基因的第2～5外显子高度保守，而第1外显子则呈高度多态。
dict.cnki.net
24. Polymorphism in Exon 6 of MAOA gene of Turpan cockfighting and Xinluoman was analyzed by PCR-SSCP.
研究采用PCR-SSCP方法分析了吐鲁番斗鸡和新罗曼鸡单胺氧化酶A基因外显子6部分序列的多态性。
www.dictall.com
25. Objective To investigate the correlation of C/T single nucleotide polymorphism at exon 17 in tyrosine kinase domain of insulin receptor gene with polycystic ovary syndrome (PCOS).
目的探讨胰岛素受体基因酪氨酸激酶区17外显子多态性与多囊卵巢综合征（PCOS）发病的关系。
dict.cnki.net
26. Objective To investigate the correlation of C/T single nucleotide polymorphism at exon 17 in tyrosine kinase domain of insulin receptor gene with polycystic ovary syndrome (PCOS).
目的探讨胰岛素受体基因酪氨酸激酶区17外显子多态性与多囊卵巢综合征（PCOS）发病的关系。
dict.cnki.net
27. Detection for the Second Exon of p16 Gene in 66 Nasopharynyeal Cancer Paraffin Imbedding Samples
?茄拾┦???癖瓯緋16基因第二外显子的检测
-- 来源 -- 网友提供
28. exon trapping system
外显子截留系统
-- 来源 -- 英汉 - 翻译参考[网络]
29. exon trapping method
外显子截留法[用于确定基因组序列中的外显子]
-- 来源 -- 英汉 - 翻译参考[网络]
30. Splice donor site-- the junction between the end of an exon and the start of the downstream introns, commencing with the dinucleotide GT.
剪接提供位--位在表现子终端和下一个表现子之间的接合点,由GT核苷对起始.
-- 来源 -- en.ohicn.com
31. Unsymmetrical PCR was used to amplify HLA-B exon 2 and 3, then labeled PCR products and hybridize with probes on the chip. Certified the typing of HLA-B by analysed and scanned the signals of hybridize through a set of computer software.
采用荧光标记引物和不对称聚合酶链反应(PCR)扩增HLA-B2、3外显子,产物与芯片探针杂交后经荧光扫描,并用特定软件分析判断阳性探针,以确定样品基因型。
-- 来源 -- 网友提供
exon
