cyclin
释义
细胞周期蛋白；
英英释义
Cyclin
Cyclins are a family of proteins that control the progression of cells through the cell cycle by activating cyclin-dependent kinase (Cdk) enzymes.
以上来源于:Wikipedia
权威例句
Cyclin is degraded by the ubiquitin pathway.Inhibitors of mammalian G1 cyclin
Cyclins and cancer II: Cyclin D and CDK inhibitors come of age
p21 is a universal inhibitor of cyclin kinases
Inhibitors of mammalian G1 cyclin-dependent kinases.
Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers
Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals
The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases.
A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4.
1. CDK and cyclin together drive the cell from one cell cycle phase to the next.
CDK和细胞周期蛋白一起使细胞从一个细胞周期到下一个细胞周期。
greatcourse.cnu.edu.cn
2. Cyclin-dependent kinase inhibitor(ICK)is a key control protein in Cell cycle that can affect the growth and development of cell.
细胞周期蛋白依赖性激酶抑制剂（ICK）是一种能够影响细胞生长和发育的重要调控蛋白。
dict.cnki.net
3. To investigate the effect of benazepril on expression of cyclin kinase inhibitor P21 CIP1 protein in renal tissue of diabetic rats.
目的：探讨苯那普利对糖尿病大鼠肾组织细胞周期蛋白激酶抑制剂P21CIP1蛋白表达的影响。
dict.cnki.net
4. METHODS: Method of multiplex polymerase chain reaction(PCR) was adopted. Cyclin D1 gene and P16 gene were amplified in the same tube, using extracted genome DNA as template.
方法：采用多重聚合酶链反应方法，以提取的基因组DNA为模板，在同一反应管中同时扩增细胞周期素D1基因和P16基因。
dict.cnki.net
5. Cyclin D1 is a key cell cycle regulator and a candidate proto-oncogene, whose deregulation has been implicated in pathogenesis of several types of cancers, including NPC.
细胞周期蛋白D1是一个关键的细胞周期调节因子和候选的原癌基因，其失调参与多种肿瘤，包括鼻咽癌的发生。
dict.cnki.net
6. Objective To observe the expression of cyclin kinase inhibitor P16 in pterygium and to investigate its effects on the pathogenesis of pterygium.
目的探讨翼状胬肉组织中细胞周期蛋白依赖性激酶抑制剂P16的表达，了解其在翼状胬肉发病机制中的作用。
www.jiaoyuda.com
7. CDK and cyclin are key molecules that control and coordinate DNA-synthesis, chromosome separation and cell division.
CDK和细胞周期蛋白是控制和协调DNA合成、染色体分离和细胞分裂的重要分子。
www.iciba.com
8. The combination of CDK and cyclin will accelerate cell cycle period, the combination of CDK and CDKI will restrain cell division.
CDK与细胞周期素结合可促进细胞周期进程，与CDKI结合则抑制细胞分裂。
dict.cnki.net
9. Objective To explore the inhibition of expression of cyclin E1 in hepatocellular carcinoma via RNA interference mediated by siRNA expressing vector.
目的探讨经载体介导的RNA干扰对肝癌细胞周期蛋白E1表达抑制效率。
dict.cnki.net
10. Results Rabbit smooth muscle cells could express cyclin D, the reactant of immune reaction was mainly located in nuclei.
结果发现，主动脉平滑肌细胞可表达细胞周期素D，其免疫反应产物主要位于细胞核内。
dict.cnki.net
11. Both clones included a DNA sequence that allow a fluorescent protein expressed in the cell to bind to cyclin D1 RNA the moment it is transcribed.
这两个克隆都包含有一段DNA序列，能在在细胞周期蛋白D1的RNA被转录的时候将荧光蛋白绑定到其上。
article.yeeyan.org
12. Cell Cycle Progression through the cell division cycle and transitions between various phases are regulated by using CDC25 phosphatases to activate specific cyclin-dependent kinase(CDK) complexes.
细胞分裂周期运行和不同时相的转换通过CDC25磷酸酶去磷酸化和激活周期蛋白依赖性激酶（CDK）复合物来调控。
dict.cnki.net
13. CONCLUSION: The high amplification of Cyclin D1 and the high deletion of P16 gene is closely related to the high activity of proliferation of lung cancer.
结论：细胞周期素D1的扩增和P16的缺失与肺癌细胞的高增殖活性密切相关。
dict.cnki.net
14. AIM To analyze the expression and significance of cyclin dependent kinase 4 (CDK4) in chondrosarcoma of the jaws.
目的分析细胞周期素依赖激酶4（CDK4）在颌骨软骨肉瘤的表达及意义。
dict.cnki.net
15. Objective To investigate the relationship between the expression of cyclin D3, cyclin E and childhood acute leukemia(AL).
目的探讨细胞周期蛋白D3、E的表达与儿童急性白血病（AL）的关系。
dict.cnki.net
16. Cyclin-dependent kinase-2 (CDK2) is one of the most important proteins of cell cycle. And the changes and effects of CDK2 in VES-induced growth inhibition in cancer cells are known little.
细胞周期素依赖性激酶2（CDK2）是目前公认的最重要的细胞周期蛋白之一，VES如何通过CDK2干扰细胞周期，调控肿瘤细胞增殖报道较少。
dj.iciba.com
17. Objective In the present study, we tried to further elucidate the expression and function of cyclin D1 in human nasopharyngeal carcinoma (NPC) cell line.
目的深入研究周期蛋白D1在鼻咽癌细胞中的表达特征及其生物学功能。
dict.cnki.net
18. Objective: To investigate the relationship between the cyclin kinase inhibitor P27 and the protective effect of quercetin on the diabetic glomerulus in rats.
目的：探讨槲皮素对糖尿病肾病的影响及该影响与肾小球周期素激酶抑制剂P27的关系。
dict.cnki.net
19. Objective To investigate the expression of cyclin-dependent kinase-2 (CDK-2) gene in SH-SY5Y cells.
目的观察细胞周期蛋白依赖性激酶-2（CDK-2）在SH-SY5Y细胞中的表达情况。
www.chemyq.com
20. Objective: Our aims were to study the expression of cyclin A in renal cell carcinoma (RCC), and to analyze the role of cyclin A in tumor cell proliferation in RCC.
目的：研究细胞周期素A在肾癌组织中的表达及其在肾癌细胞增殖中的作用。
www.dictall.com
21. Cyclin B1, Rabbit anti-Hamster, Mouse, Hamster, Human.
周期素B1，兔抗仓鼠，小鼠，仓鼠，人。
www.advtechind.cn
22. To test the method, they created two clones of a human embryonic kidney cell line with an engineered version of the gene cyclin D1, which controls the cell cycle.
为了测试这种方法，他们克隆了两个人类胚胎肾脏细胞株，在其中加入了改良版本的细胞周期蛋白D1（这种蛋白可以控制细胞周期）。
article.yeeyan.org
23. AIM: To investigate whether endothelin-1 (ET-1) can promote human umbilical artery smooth muscle cell(HUASMC) proliferation through pathway of extracellular signal-regulated kinase(ERK) and cyclin D1.
目的：探讨内皮素-1是否通过细胞周期蛋白质D1与细胞外调节蛋白激酶通路促进人脐动脉平滑肌细胞增殖。
www.dictall.com
24. MAIN OUTCOME MEASURES: ① Amplificative result of cyclin D1 and P16 in the pathological tissue of the patients with lung cancer.
主要观察指标：①肺癌患者病理组织中细胞周期素D1和P16的基因扩增结果。
dict.cnki.net
25. Objective: To study the expression of cyclin dependant kinase 4(CDK4) protein in oral carcinogenesis.
目的：探讨CDK4蛋白在口腔粘膜癌变过程中表达的变化规律。
www3.chkd.cnki.net
26. "We think that the radiosensitization is primarily due to cyclin D1, " Dr. Dicker says.
“我们认为放射敏感性主要与细胞周期蛋白D1相关，”狄克博士说。
news.dxy.cn
27. Objective:To investigate the expressions and significance of cyclin-dependent kinase 2 (CDK2) and heat shock protein 60 (HSP 60) in human cervical carcinoma.
目的 ：研究人子宫颈癌组织中细胞周期蛋白依赖性激酶 （CDK）2、热休克蛋白 （HSP）60的表达 状态 ，并探讨它们与宫颈癌的关系。
dj.iciba.com
28. Cyclin D1 is frequently over-expressed in cancers and its overexpression can be attributed to many factors including increased transcription, translation, and protein stability.
细胞周期蛋白D1在癌症中经常过表达，可引起其过表达的因素很多，包括增加转录，翻译和蛋白质的稳定性。
www.xinkexue.com
29. Cyclin D1 is frequently over-expressed in cancers and its overexpression can be attributed to many factors including increased transcription, translation, and protein stability.
细胞周期蛋白D1在癌症中经常过表达，可引起其过表达的因素很多，包括增加转录，翻译和蛋白质的稳定性。
www.xinkexue.com
30. Objective] To construct recombinant expressing Cyclin D1 and CDK4 proteins.
【目的】建表达人细胞周期蛋白D1及细胞周期蛋白激酶CDK4融合蛋白的重组体。
-- 来源 -- dict.cnki.net
31. Protein serine theronine phosphatase inhibitor or cyclin dependent kinase( CDK) inhibitors could abolish the enhancement.
而蛋白丝氨酸苏氨酸磷酸酯酶抑制剂以及细胞周期蛋白依赖性激酶(DK)制剂可阻断该凋亡敏感性增强效应。
-- 来源 -- dict.cnki.net
32. The P16 、RB、CYCLIN D1 /CDK4 、CDK6, pathway as a functional unit,deregulation of this checkpoint way represents a common step in the multistep progression of sporadic malignant tumors, as well as P16 regulation occurs via RB dependent pathway.
由P16、RB、cyclinD_1,及CDK_4、CDK_6构成的调控细胞周期的负反馈通路作为细胞周期G1/S期的一个重要调节点,它的失调是导致肿瘤恶性发展的重要因素。 RB可能对P16的表达具有调控作用。
-- 来源 -- 网友提供
cyclin
