Flutamide
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释义
N-3-（三氟甲基-4硝基）苯基异丁酰胺；缓退瘤；氟他米特；
权威例句
Flutamide withdrawal syndrome: its impact on clinical trials in hormone-refractory prostate cancerGoserelin acetate and flutamide versus bilateral orchiectomy: a phase III eortc trial (30853)
Bilateral orchiectomy with or without flutamide for metastatic prostate cancer.
Bilateral Orchiectomy with or without Flutamide for Metastatic Prostate Cancer — NEJM
A controlled trial of leuprolide with and without flutamide in prostatic carcinoma.
Effect of flutamide and metformin administered alone or in combination in dieting obese women with polycystic ovary syndrome.
Prostate specific antigen decline after antiandrogen withdrawal: the flutamide withdrawal syndrome.
Comparison of spironolactone, flutamide, and finasteride efficacy in the treatment of hirsutism: a randomized, double blind, placebo...
Polycystic ovarian syndrome: evidence that flutamide restores sensitivity of the gonadotropin-releasing hormone pulse generator to i...
Comparison of the effects of the 5 alpha-reductase inhibitor finasteride and the antiandrogen flutamide on prostate and genital diff...
1. We established an androgen-independent prostate cancer cell line induced by the combination of flutamide and androgen-free environment after long-term culture in vivo.
采用氟他胺联合去雄激素环境联合诱导培养的方法在体外建立一株雄激素非依赖性前列腺癌细胞系。
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2. CONCLUSIONS Androgen can autoregulate the expression of androgen receptor in MCF-7 breast cancer cell line. Flutamide and hydroxyflutamide up regulate the expression of androgen receptor.
结论MCF-7乳腺癌细胞株中雄激素受体存在自动调节，氟他胺和羟基氟他胺上调雄激素受体的表达。
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3. AIM: To study the atrophy and apoptosis effect of flutamide (Flu) and 2 hydroxyflutamide (HF) on the benign prostatic hypertrophy (BPH) of rats.
目的：研究氟他胺与2 羟基氟他胺对诱导的前列腺增生大鼠前列腺萎缩和细胞凋亡的作用。
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4. From highly Pare m-trifluoromethyl aniline, the Flutamide is prepared by acylation with isobutyl chloride and nitration with assistant S.
以高纯度间三氟甲基苯胺为原料，经异丁酰氯酰化，再在助剂S存在下进行硝化制得氟他胺。
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5. OBJECTIVE To develop an HPLC-MS/MS method for the determination of 2-hydroxyflutamide in human plasma and evaluate the bioequivalence of flutamide tablets.
目的建立人血浆中2-羟基氟他胺的HPLC-MS/MS测定法，研究氟他胺片生物等效性。
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6. Objective To investigate the effects of flutamide on hyperplasia of prostate and its mechanism.
目的探讨氟硝丁酰胺抑制前列腺增生的作用及其机制。
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7. Conclusion Inhibition of flutamide on hyperplasia of prostate is associated with antagonizing the effect of androgen.
结论氟硝丁酰胺通过拮抗雄激素作用而抑制前列腺增生。
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8. Purpose :To evaluate the efficacies of orchiectomy plus flutamide and pure orchiectomy in the treatment of metastatic prostatic cancer.
目的：评估睾丸切除联合缓退瘤与单纯睾丸切除治疗进展性前列腺癌的疗效。
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9. Objective To investigate the effect of flutamide on laryngeal carcinoma cell lines HEP-2 apoptosis.
目的观察氟硝丁酰胺对喉鳞癌细胞株HEP2的生长调控作用。
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10. Furthermore, androgen up-regulation of intracellular AR protein was partially inhibited (50%) by nonsteroidal androgen antagonist, flutamide.
雄激素拮抗剂氟他胺也能够部分抑制（5 0 % ）睾酮对细胞内AR蛋白水平的上调作用。
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11. Objectives: To observe the effect of removal of testicular essence combined with therapy of Flutamide in patients with advanced prostate cancer .
目的：观察睾丸实质切除联合缓退瘤治疗晚期前列腺癌的疗效。
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12. A complete or partial response to maximal androgen blockade was observed in 65%, being significantly higher than that in flutamide alone (39%).
有效率（完全缓解率加部分缓解率）治疗组为65％，对照组为39％。
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13. Purpose:To investigate the effect of combined castration and flutamide therapy in patients with advanced prostate cancer.
目的：探讨缓退瘤治疗晚期前列腺癌的效果。
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14. Abstr: Objective To investigate and compare the treatment effects of bicalutamide and flutamide on castrated resistant prostate cancer(CRPC) in advanced stage.
文章摘要：目的探讨比卡鲁胺与氟他胺治疗晚期去势抵抗性前列腺癌的疗效比较。
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15. Methods Castration was performed on 8 patients with prostate cancer, followed by flutamide treatment.
目的探讨去势手术加缓退瘤治疗前列腺癌的效果。
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16. Methods Castration was performed on 8 patients with prostate cancer, followed by flutamide treatment.
目的探讨去势手术加缓退瘤治疗前列腺癌的效果。
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17. Methods: Radical(2 patients) or palliative(5) protatectomy were performed in7 late prostatic cancer3～6 months after castration and pharmacotheray with Flutamide and DES.
方法：对7例晚期前列腺癌患者行双睾丸切除术后服用缓退瘤和乙烯雌酚3～个月再行根治性(例)姑息性(例)列腺切除术。
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Flutamide
