histone
n. [生化] 组蛋白
n.
组蛋白；
英英释义
histone[ 'histəun ]
n.a simple protein containing mainly basic amino acids; present in cell nuclei in association with nucleic acids
双语例句
用作名词(n.)
The histone code will not be easy to crack.
组织蛋白的密码不是那么容易破解的。
权威例句
Translating the histone codeTranslating the Histone Code
Allis CD: Translating the histone code
Translating the Histone Code \r10.1126/science.1063127
The language of covalent histone modifications.
Specificity of anti-histone antibodies in systemic lupus erythematosus
High-resolution profiling of histone methylations in the human genome.
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139.
Strahl, B. D. & Allis, C. D. The language of covalent histone modifications. Nature 403, 41-45
Small-molecule inhibitors of histone deacetylase for the treatment of cancer and non-cancer diseases: a patent review (2011 - 2013).
histone (n.)
1885, from German histon (1884); see histo- + -one.
1. Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to the carboxy terminus of the human histone H3 protein.
该单克隆抗体是采用合成的与人组蛋白H3蛋白羧基基端肽段免疫动物而生产的。
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2. It ensures that the H4 histones have plenty of attached acetyl groups, so the DNA wrapped around the histone once again becomes available for transcription.
它保证了H4组蛋白有大量的乙酰基团粘附其上，所以环绕在组蛋白上的DNA能再次被翻译。
zuci.chaziwang.com
3. DNA methylation catalyzed by DNA methyltransferases interacts with histone modification to inhibit gene transcription, induce gene silencing at the participation of many regulators.
DNA甲基化由DNA甲基转移酶催化，在多种调节因子的参与下，与组蛋白修饰相互作用，抑制基因转录，导致基因沉默。
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4. The chromatin remodeling and histone acetylation were associated with transcription activation.
真核基因活化与染色质的重建及组蛋白的乙酰化相关。
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5. To adapt to various states of chromatin, corresponding histone variants are incorporated in nucleosome, and certain modifications also occur on the variants tails.
对于不同状态的染色质，核小体中会组装入相应的组蛋白变体，并且各种组蛋白变体的尾部也能发生多种修饰。
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6. The methylation of histone lysine is an important covalent modification at its tails and plays a key role in epigenetic regulation.
组蛋白赖氨酸甲基化是组蛋白尾段发生的一种重要共价修饰，在基因的表观遗传转录调控中起着关键的作用。
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7. The discovery of the histone lysine demethylases has strongly demonstrated that histone lysine methylation is a reversible epigenetic modification.
随着组蛋白赖氨酸去甲基化酶的发现，证实组蛋白赖氨酸甲基化是一个可以逆转的组蛋白表遗传修饰。
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8. They have discovered an enzyme - histone deacetylase 5 (HDAC5) - has a significant influence on the effect of the hormone.
他们发现，大脑中有一个“开关”控制瘦素的作用，它就是一种名为组蛋白去乙酰化酶5（HDAC5）的酶。
language.chinadaily.com.cn
9. Aberrant methylation may be the most common mechanism of inactivating cancer-related genes in lung cancer, and histone modification may be closely associated with DNA methylation.
表遗传学机制在肺癌的形成中占据重要地位，包括DNA的甲基化和组蛋白修饰，肺癌中与癌形成有关基因的失活多与异常甲基化有关，并且组蛋白修饰和甲基化紧密联系着。
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10. The discovery of the histone lysine demethylases has strongly demonstrated that histone lysine methylation is a reversible epigenetic modification.
组蛋白赖氨酸甲基化是组蛋白尾段发生的一种重要共价修饰，在基因的表观遗传转录调控中起着关键的作用。
www.dictall.com
11. The methylation of histone lysine is an important covalent modification at its tails and plays a key role in epigenetic regulation.
随着组蛋白赖氨酸去甲基化酶的发现，证实组蛋白赖氨酸甲基化是一个可以逆转的组蛋白表遗传修饰。
www.dictall.com
12. Specific measurement of activity/inhibition of H3-K9 histone methyltransferases.
专一性检测H3-K9组蛋白甲基转移酶活性/抑制性。
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13. Phospho-histone H3 is a mitosis-specific antibody, which was already proven to facilitate mitotic count in melanoma and other tumors.
磷酸化组蛋白H3是核分裂特异性抗体，被证实在黑色素瘤和其他肿瘤中有助于计数核分裂。
literature.ipathology.cn
14. Modifications of chromatin structure by acetylation/deacetylation of the histone proteins play a central role in the regulation of gene expression.
组蛋白乙酰化/去乙酰化修饰染色质在基因表达中起关键作用。
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15. Immunohistochemical analysis of paraffin-embedded human colon carcinoma using Histone H2B (D2H6) Rabbit mAb in the presence of control peptide (left) or antigen-specific peptide (right).
免疫组化分别检测在controlpeptide（左图）或抗原特异性多肽（右图）存在的情况下石蜡包埋的人结肠癌，所使用的抗体为HistoneH2B （D2H6）RabbitmAb。
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16. Immunohistochemical analysis of paraffin-embedded human colon carcinoma using Histone H2B (D2H6) Rabbit mAb in the presence of control peptide (left) or antigen-specific peptide (right).
免疫组化分别检测在controlpeptide（左图）或抗原特异性多肽（右图）存在的情况下石蜡包埋的人结肠癌，所使用的抗体为HistoneH2B （D2H6）RabbitmAb。
www.cst-c.com.cn
17. The histone code will not be easy to crack.
看来，组织蛋白的密码不是那麽容易破解的。
-- 来源 -- 210.71.44.154
18. A nucleoprotein whose protein component is a histone.
核组蛋白蛋白成分是组蛋白的核蛋白
-- 来源 -- 英汉 - 短句参考
19. histone insulin
组朊胰岛素
-- 来源 -- 英汉 - 翻译参考[网络]
20. The chromatin remodeling and histone acetylation were associated with transcription activation.
真核基因活化与染色质的重建及组蛋白的乙酰化相关。
-- 来源 -- dict.cnki.net
21. histone modifficatio
组织蛋白改良
-- 来源 -- 英汉 - 翻译参考[网络]
22. octameric histone
八聚合体组蛋白，组蛋白八聚体
-- 来源 -- 英汉 - 翻译参考[网络]
23. histone octamer
组蛋白八聚体
-- 来源 -- 英汉 - 翻译参考[网络]
24. "Histone: Any of a class of rather simple proteins occurring in cell nuclei and in combination with DNA to form nucleoproteins. They can be obtained from both plants and animals. Unlike most proteins, they dissolve readily in water. They were discovered c. 1884."
组蛋白： 任何一种存在于细胞核内或者与去氧核糖核酸结合成核蛋白的相当简单的蛋白质。它们可以从植物以及动物内得到。与大多数蛋白质不同，它们很容易溶解于水。它们是在1884年发现的。
-- 来源 -- 英汉 - 翻译样例 - 自然
25. histone repression
组蛋白阻遏
-- 来源 -- 英汉 - 翻译参考[网络]
26. DNA wraps around histone spools to form a rosarylike chain, which is then twisted into a bundle[ see illustration on opposite page].
DNA缠绕在组织蛋白构成的线轴上，形成类似念珠的链子，然后再绕成一束（见上页〈因音量的控制〉。
-- 来源 -- 210.71.44.154
histone
