methylation
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释义
甲基化作用；
英英释义
Methylation
In the chemical sciences, methylation denotes the addition of a methyl group to a substrate or the substitution of an atom or group by a methyl group. Methylation is a form of alkylation with a methyl group, rather than a larger carbon chain, replacing a hydrogen atom.
以上来源于:Wikipedia
词组短语
dna methylation甲基化；DNA甲基化
双语例句
用作名词(n.)
However, then injecting them with a drug to inhibit methylation seemed to erase any memory of the shock.
然而，在给它们注射了抑制甲基化作用的药物后，它们对于电击的记忆似乎就完全被消去了。
权威例句
DNA methylation patterns and epigenetic memoryMethylation of histone H3 lysine 9 creates a binding site for HP1 proteins.
Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.
Bird AP. DNA methylation patterns and epigenetic memory. Genes Dev 16: 6-21
Genome-scale DNA methylation maps of pluripotent and differentiated cells
CpG-rich islands and the function of DNA methylation.
Role of histone H3 lysine 27 methylation in Polycomb-group silencing.
Whole-Genome Analysis of Histone H3 Lysine 4 and Lysine 27 Methylation in Human Embryonic Stem Cells
DNA Methyltransferases Dnmt3a and Dnmt3b Are Essential for De Novo Methylation and Mammalian Development
Clinical Trial Substantiates the Predictive Value of O-6-Methylguanine-DNA Methyltransferase Promoter Methylation in Glioblastoma Pa...
1. This methylation of GR appears to make the individual more tuned in or sensitized to stress, so they will react to it quicker mentally and hormonally.
这种GR的甲基化似乎使个体对压力更加了解或敏感，他们会在心理上和荷尔蒙分泌上反应更快。
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2. Oxidative methylation of toluol to styrene is a new process.
甲苯氧化甲基化合成苯乙烯是一种新工艺。
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3. Methylation % switches genes off.
甲基化作用关闭基因。
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4. The most common mechanism is methylation.
最常见的机能是甲基化。
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5. Methylation of chromatin causes it to condense.
染色质甲基化后会出现凝缩。
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6. The ability to track methylation is thus scientifically important.
追踪甲基化的能力因而在科学上有其重要性。
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7. Methylation typically silences genes so that they are not expressed.
甲基化作用代表性的抑制了基因，因此他们没有被表达。
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8. Can altered methylation patterns be somehow detected in blood samples?
甲基化样品能否在血液样本被发现？
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9. Various factors can influence methylation, including environmental conditions.
很多因素都可以影响甲基化，包括环境条件。
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10. "DNA methylation in the kidney is different from DNA methylation in the liver," he says.
“肾脏内的DNA甲基化不同于肝脏内的，”他说。
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11. When a methyl group attaches to a specific spot on a gene - a process called DNA methylation.
甲基附加到基因上某个特殊点的过程，称为DNA甲基化。
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12. They found 88 sites on the men’s DNA where the amount of methylation correlated with their ages.
在这些人的大量甲基化了的DNA上，有88个点与他们的年龄关系密切。
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13. They found 88 sites on the men's DNA where the amount of methylation correlated with their ages.
在这些人的大量甲基化了的DNA上，有88个点与他们的年龄关系密切。
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14. The team looked at methylation, in which a methyl group is placed onto cytosine in DNA sequences.
工作小组关注甲基化作用，是指一个甲基群被放在DNA序列的胞嘧啶上面。
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15. Here, we review the role of epigenetics in aging and longevity with a focus on DNA methylation.
这里，我们回顾了表观遗传学在衰老和长寿中的作用，集中在DNA甲基化。
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16. And in rats, such methylation makes young animals especially sensitive to stress, and also fearful of novelty.
而老鼠试验表明，这样的甲基化过程让幼小动物对压力尤其敏感，对新鲜事物也感到恐惧。
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17. But the patterns of methylation change as we grow older. Which was a clue that measuring methylation might give away age.
但是甲基化的发生模式会随着我们年龄的增加发生变化，这也就为通过测定甲基化确定人体年龄提供了可能。
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18. Our data provide new insights into the function of histone methylation and chromatin organization in genome function.
我们的数据提供了一个在基因组功能中组蛋白甲基化和染色质组织的新观点。
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19. Whether cytosine methylation is the explanation for this difference has yet to be tested, but something is clearly happening.
胞嘧啶甲基化是否能够解释这种差异还有待考察，但是的确是有些什么东西存在着。
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20. Epigenetics is a type of gene regulation that can be passed from a cell to its daughters. The most common mechanism is methylation.
外因遗传是一种可以传给下一代细胞的基因调控过程，最常见的方式是通过甲基化作用来完成，该作用可以让甲基（由一个碳原子和三个氢原子组成）附着于腺嘌呤或胞嘧啶上。
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21. But in the daughters of obese fathers, the level of methylation of this gene was around 25% of the level seen in the control daughters.
但在父亲肥胖的雌鼠身上，该基因的甲基化水平仅占对照组雌鼠的25%左右。
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22. Methylation is an epigenetic modification to one's DNA that changes a gene's activity, generally reducing that activity within the genome.
甲基化作用是对DNA的后天修改，并改变基因活动，通常是在基因组内减少这个活动。
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23. When you use animal models and do the things that are commonly done in assisted reproduction, the answer is yes—it affects DNA methylation.
“如果你在动物模型上模拟辅助生殖你会发现答案是肯定--它能影响DNA的甲基化”。
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24. The process, known as DNA methylation, is one mechanism of epigenetic change, heritable change that does not alter the sequence of DNA itself.
该过程被成为DNA甲基化，是表观遗传变化的一种，属于不会改变DNA序列的可遗传变化。
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25. The plants were derived from two Arabidopsis parents with essentially identical genomes, but with one having a mutated DDM1 DNA methylation gene.
这些植株源自两棵基因几乎相同的拟南芥，但其中一棵含有突变的DDM1甲基化DNA。
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26. The presumption is that the pattern of methylation, by controlling which proteins are manufactured, helps determine what type of cell is produced.
推论是甲基化模式通过控制蛋白质的合成从而决定形成什么样的细胞.
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27. Andrew Hudson at the University of Edinburgh says there is a clear implication that "DNA methylation and epigenetic changes are important in evolution."
爱丁堡大学的AndrewHudson表示，这明显意味着“DNA甲基化和表观基因变异在进化中是非常重要的”。
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28. Cancer cells exploit this process, putting some genes in "cold storage" or "turned off" by modifying the cell DNA in a process known as methylation.
癌细胞正是利用这一过程来发挥作用，即通过甲基化作用修饰细胞DNA，从而将一些基因打入“冷宫”或关闭基因的表达。
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29. Moreover, the methylation patterns were clustered together in large swaths of DNA, suggesting an epigenetic pattern linked to humans’ early environments.
而且，甲基化的模式在DNA长链中被聚集到一起，显示了与早期环境相关的后天模式。
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30. Discussing the relations of DNA methylation and gene transcriptional silencing takes on important significances for the study of many human diseases.
探讨DNA甲基化与基因转录抑制之间的关系，对许多人类疾病的研究具有重要意义。
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methylation
