egr-1
释义
[医]early growth response gene-1；
英英释义
EGR1
EGR-1 (Early growth response protein 1) also known as Zif268 (zinc finger protein 225) or NGFI-A (nerve growth factor-induced protein A) is a protein that in humans is encoded by the EGR1 gene.
以上来源于:Wikipedia
权威例句
Egr-1, a master switch coordinating upregulation of divergent gene families underlying ischemic stress.The zinc finger transcription factor Egr-1 is essential for and restricts differentiation along the macrophage lineage.
Production of hydrogen peroxide by transforming growth factor-beta 1 and its involvement in induction of egr-1 in mouse osteoblastic...
Lipopolysaccharide induction of the tumor necrosis factor-alpha promoter in human monocytic cells. Regulation by Egr-1, c-Jun, and N...
Early Growth Response Protein 1 (Egr-1): Prototype of a Zinc-finger Family of Transcription Factors
Regulation of life and death by the zinc finger transcription factor Egr-1.
Egr-1-Induced Endothelial Gene Expression: A Common Theme in Vascular Injury
The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling
Egr-1 Regulates Autophagy in Cigarette Smoke-Induced Chronic Obstructive Pulmonary Disease
Luteinizing hormone deficiency and female infertility in mice lacking the transcription factor NGFI-A (Egr-1).
1. Egr-1 is a radiation-inducible transcription factor.
系-具有辐射诱导特性的转录因子。
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2. FGF-2, a potent agonist of Egr-1, plays an important role vascular repair after injury.
作为早期生长反应基因-1的增效剂，纤维生长因子-2 在损伤后的血管修复中起着重要的作用。
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3. In the same (endothelial denudation) model, we found that Egr-1 is expressed later by migrating SMCs.
在同样的内皮剥脱模型中，我们发现早期生长反应基因- 1由随后内移的平滑肌细胞表达。
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4. For example, ED5 reduces cortical Egr-1 mRNA expression and interstitial fibrosis in rats 7 days after renal obstruction (unilateral ureteral ligation) and delivery by electroporation.
例如，ED5可以减少小鼠尿路梗阻（单侧输尿管结扎）或通过电穿孔法切除肾脏7天后皮质早期生长反应基因-1信使RNA表达和间质纤维化。
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5. The expression of EGR family members is induced by growth factors, with EGR1 expression being induced by NGF (1, 2).
EGR家族成员的表达可被生长因子诱导，EGR1的表达可被神经生长因子(NGF)诱导(1,2)。
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6. EGR family members are transcriptional factors that contain three repetitive zinc finger DNA binding domains which bind to EGR response elements (er) to regulate target gene expression (1).
EGR的家庭成员是包含三个重复的锌指dna结合域的转录因子，它可以EGR响应元素(ER)，调节靶基因的表达(1)。
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7. Objective to study the effect of ionizing radiation on the expression of liposome mediated GFP reporter gene drived by EGR - 1 gene promoter and CMV promoter, respectively in hepatoma 7402 cells.
目的研究电离辐射调控脂质体介导的EGR - 1基因启动子、CM V启动子驱动的GF P报告基因在人肝癌7402细胞内的表达。
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8. Objective to study the effect of ionizing radiation on the expression of liposome mediated GFP reporter gene drived by EGR - 1 gene promoter and CMV promoter, respectively in hepatoma 7402 cells.
目的研究电离辐射调控脂质体介导的EGR - 1基因启动子、CM V启动子驱动的GF P报告基因在人肝癌7402细胞内的表达。
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egr-1
