penetrance

英式音标：['penətrəns]

美式音标：['penətrəns]

词汇分类：遗传学 Genetics,遗传学词汇Genetics Glossaries,医学文献常见生词（2）,医学文献常见生词（1）,肿瘤学（百歌医学单词USMLE）,医学文献常见单词（3）

词义：

n.

外显率；

英英释义

Penetrance

Penetrance in genetics is the proportion of individuals carrying a particular variant of a gene (allele or genotype) that also express an associated trait (phenotype). In medical genetics, the penetrance of a disease-causing mutation is the proportion of individuals with the mutation who exhibit clinical symptoms.

以上来源于:Wikipedia

用法：

权威例句

Low penetrance in the long-QT syndrome: clinical impact

Meta-Analysis of BRCA1 and BRCA2 Penetrance

Penetrance of the fragile X-associated tremor/ataxia syndrome in a premutation carrier population.

Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations.

Hepatocellular carcinoma and the penetrance of HFE C282Y mutations: a cross sectional study.

Prevalence and Penetrance of Germline BRCA1 and BRCA2 Mutations in a Population Series of 649 Women with Ovarian Cancer

Phenotype, genotype, and worldwide genetic penetrance ofLRRK2-associated Parkinson's disease: a case-control study

A new model for prediction of the age of onset and penetrance for Huntington's disease based on CAG length

Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Cons...

Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles

造句：

1. The suitable nuclear gene type is very important to raise the penetrance of multi-ovary.

因此，欲提高小麦多子房性状表达的外显率，选择合适核型至关重要。

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2. Outline lighting, projection lighting, internal penetrance lighting and intelligent lighting were introduced.

重点介绍轮廓照明、投光照明、内透照明和智能照明。

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3. This article has introduced a kind of technology about coal gas is exploited. The penetrance of the coal gas will be improved greatly and the output of the…

论文介绍了一种煤层气开采技术，利用该项技术可以大大提高煤层气的渗透性，增加煤层气的产量。

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4. Mechanisms of antibiotics resistance includes: (1) target site modification; (2) production of inactive enzymes; (3) decrease of drugs penetrance; (4) expression of efflux pumps.

抗菌药物耐药机制包括：(1)靶位修饰；(2)产灭活酶；(3)药物渗透力下降；(4)外排泵表达。

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5. Mechanisms of antibiotics resistance includes: (1) target site modification; (2) production of inactive enzymes; (3) decrease of drugs penetrance; (4) expression of efflux pumps.

抗菌药物耐药机制包括：(1)靶位修饰；(2)产灭活酶；(3)药物渗透力下降；(4)外排泵表达。

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