ligand-gated

英式音标：['lɪɡəndɡ'eɪtɪd]

美式音标：['lɪɡəndɡ'eɪtɪd]

词汇分类：神经系统（百歌医学单词USMLE）,医学英语词汇大集合,医学英语长难词语

词义：

释义

[医]配基门控；

用法：

权威例句

Sequence and functional expression of the GABA A receptor shows a ligand-gated receptor super-family

A new class of ligand-gated ion channel defined by P2x receptor for extracellular ATP.

An excitatory amino-acid transporter with properties of a ligand-gatedchloride channel

New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor.

An excitatory amino-acid transporter with properties of a ligand-gated channel. Nature, 375, 599-603

Insect olfactory receptors are heteromeric ligand-gated ion channels.

A ligand-gated association between cytoplasmic domains of UNC5 and DCC family receptors converts netrin-induced growth cone attracti...

Drosophila odorant receptors are both ligand-gated and cyclic-nucleotide-activated cation channels.

Valera, S.et al. Anew class of ligand-gated ion channel defined by P2X receptor for extracellular ATP. Nature 371, 516-519

X-ray structure of a prokaryotic pentameric ligand-gated ion channel

造句：

1. In 1990s, molecular biological approach has led to a series of cloning and functional expression of ligand-gated P2X receptors and G-protein coupled P2Y receptors.

90年代，采用分子生物学手段，一系列配体门控的P2 X受体及G蛋白耦联的P 2y受体被克隆及功能表达。

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2. This divalent cation is released from presynaptic vesicles into the synaptic cleft upon neuronal activity and acts as a modulator of many ligand-gated ion channels.

锌离子随着神经元的活动从突触前膜的囊泡中释放到突触间隙，对突触内受体进行调控。

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3. Because the binding of the neurotransmitter (ligand) to the receptor activates these ion channels, they are called ligand-gated channels to distinguish them from voltage-gated channels.

因为神经递质和受体结合（配位）启动了这些离子通道， 所以他们被称为配位门通道，以区别于电压门通道。

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4. Methods: the two-electrode voltage clamp recording technique was used to observe the ligand-gated and voltage-gated ion channel currents expressed in Xenopus laevis oocytes without follicles.

方法：在去除滤泡膜的非洲爪蟾卵母细胞上，建立双电极电压钳记录技术，并使用该技术观察爪蟾卵母细胞表达的内源性递质门控性和电压门控性离子通道电流。

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5. Methods: the two-electrode voltage clamp recording technique was used to observe the ligand-gated and voltage-gated ion channel currents expressed in Xenopus laevis oocytes without follicles.

方法：在去除滤泡膜的非洲爪蟾卵母细胞上，建立双电极电压钳记录技术，并使用该技术观察爪蟾卵母细胞表达的内源性递质门控性和电压门控性离子通道电流。

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