Hemophiliaresults when a gene fails to produce the protein needed for the blood

Hemophilia（血友病）resultswhen a gene fails to produce the protein needed for the blood to clot, orchange from a liquid to a solid. The fault gene is passed from parents tochildren. People with hemophilia suffer uncontrolled bleeding. This can resultin pain, tissue swelling（肿胀）andpermanent damage to joints and muscles.

One in every ten thousand males has the mostcommon kind of hemophilia. It’s extremely rare for females to have it. Patientscan be treated with the missing clotting substance. They generally can leadnormal lives.

Scientists say gene treatment may be apossible way to cure hemophilia in the future. Researchers consider hemophiliathe best disease for gene treatment because it is caused by a single faultgene. Also, only a small increase in the missing clotting substance couldprovide good results. They tested gene treatment in six patients with severehemophilia.

First, they removed skin cells from thepatients’ arms. The researchers grew the cells in the laboratory. They addedcopies of the needed gene taken from healthy people. Then they created hundredsof millions of genetically changed cells. They placed these cells into thepatients’ stomachs. After four months, the amount of blood clotting substancein the blood increased in four of the six patients. Some of the patientsreported a decrease in bleeding problems. However, ten months later, theclotting substance was no longer in the patients’ blood. It is not clear if theimplanted cells died or the added genes stopped working.

The researchers say the study showed thatgene treatment is safe for people with the most common kind of hemophilia. Butothers expressed concern about the treatment because the effects were onlytemporary.

1. Whichof the following statements is NOT true about hemophilia?

A. It iscaused by a fault gene and is passed from parents.

B. Itsuffers uncontrolled bleeding.

C. Peoplewith hemophilia don’t have any physical damage and can lead normal lives.

D. Itdoesn’t succeed in making protein needed for blood to form into clots.

2. Peoplewith hemophilia can live normally when______.

A. theyare treated with the missing clotting substance

B. theyaccept the scientists’ help

C. goodcopies of gene are placed in their bodies

D. theyplace some genetically changed cells into their stomachs

3. Bycarrying out the experiment, scientists conclude that______.

A. theeffects of treatments are excellent and last long

B. genetreatment is a safe and possible way to treat hemophilia

C. peoplewith hemophilia can recover completely with gene treatment

D.hemophilia is a disease that can be treated easily

4. Whichof the following can be the title of the passage?

A.Whether people with hemophilia can live a normal life

B. How tocontrol the bleeding for the patients

C. Howthe researchers remove skin cells from patients and place these cells into thepatients

D. Thegene treatment to the hemophilia

试题答案

答案：1C2A3B4D