aldose reductase
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释义
[医]醛糖还原酶；
双语例句
It is prospective that new drug development with aldose reductase as a potential target can achieve significant progress.
预计以醛糖还原酶为靶点的新药研究和开发将取得重要进展。
Using epalrestat as a control, the aldose reductase inhibitory activities of the compounds obtained were evaluated on rat lens aldose reductase in vitro.
以依帕司他为阳性对照药，采用大鼠晶状体醛糖还原酶对目标化合物醛糖还原酶抑制活性进行初步评价。
权威例句
Aldose Reductase Inhibitors and Late Complications of DiabetesAldose reductase and the role of the polyol pathway in diabetic nephropathy.
ISOLATION AND PROPERTIES OF LENS ALDOSE REDUCTASE.
Aldose reductase in glucose toxicity: a potential target for the prevention of diabetic complications
Autoimmunity in Membranous Nephropathy Targets Aldose Reductase and SOD2
Role of aldose reductase and oxidative damage in diabetes and the consequent potential for therapeutic options.
Cardiac abnormalities in diabetic patients with neuropathy: effects of aldose reductase inhibitor administration.
An unlikely sugar substrate site in the 1.65 A structure of the human aldose reductase holoenzyme implicated in diabetic complicatio...
ChemInform Abstract: Antidiabetic Principles of Natural Medicines. Part 2. Aldose Reductase and α‐Glucosidase Inhibitors from Braz...
Semi-quantitation of mRNA by polymerase chain reaction. Levels of oxidative defense enzymes and aldose reductase in rat lenses cultu...
1. Aldose reductase (ar) plays an important role in sugar cataract and other complications of diabetes.
醛糖还原酶(AR)在糖性白内障和其它糖尿病并发症的发病中起着关键性的作用。
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2. Pharmacological experiments of Chinese herbal medicine were focused on antioxidant effect and inhibiting aldose reductase and decreasing apoptosis of lens epithelial cell.
中药制剂的实验药理研究主要集中在抗氧化作用、抑制醛糖还原酶作用和抑制晶状体上皮细胞凋亡方面。
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3. Results compared with the control group, the aldose reductase gene was down-regulated in the captopril intervention group.
结果与对照组相比，干预组醛糖还原酶基因表达下调。
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4. Aldose reductase is an enzyme that is normally present in the eye and in many other parts of the body.
醛式糖还原酶是通常是存在在眼睛和在许多其它身体部位的酵素。
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5. Aldose reductase is a key rate?limiting enzyme in the pathway, while aldose reductase inhibitors can inhibit the pathway and alleviate the symptoms of diabetic complications.
醛糖还原酶是多元醇代谢通路中的限速酶，醛糖还原酶抑制剂能有效抑制此通路，减慢或改善糖尿病并发症。
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6. This review mainly gives a brief account of the progress of research on aldose reductase inhibitors from microorganisms.
本文主要概述了微生物来源的醛糖还原酶抑制剂的研究进展。
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7. The effect of ICI 128436, an aldose reductase inhibitor on the sorbitol metabolism in the mouse pancreatic islets during in vitro culture was observed.
观察了一种醛糖还原酶抑制剂（ICI 128436）对小鼠胰岛体外培养时山梨醇代谢的影响情况。
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8. Objective To optimize the the NADPgenerating fluorimetric method for aldose reductase (AR) activity.
目的找出优化NADP生成荧光法测定红细胞醛糖还原酶(AR)活性的方案。
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9. Objective To investigate the relationship between aldose reductase-like-1 (ARL-1) gene and drug resistance in human liver carcinoma cells.
目的探讨醛糖还原酶相似基因- 1 (ARL - 1基因)与人肝癌细胞耐药性的关系。
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10. Drugs that prevent or slow (inhibit) the action of aldose reductase are being studied as a way to prevent or delay these complications of diabetes.
人们正在研究防止或减缓(阻断)醛式糖还原酶的药物，用以防止或延迟糖尿病综合症动。
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11. The phosphorylation assay proves that aldose reductase is the substrate of insulin-receptor tyrosine kinase and the Tyr(40) and Tyr(49) are phosphorylated by the kinase.
在试管内，未磷酸化的醛糖还原酶和磷酸化的醛糖还原酶的动力学常数无差异，而细胞内的情况有待于进一步研究。
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12. The phosphorylation assay proves that aldose reductase is the substrate of insulin-receptor tyrosine kinase and the Tyr(40) and Tyr(49) are phosphorylated by the kinase.
在试管内，未磷酸化的醛糖还原酶和磷酸化的醛糖还原酶的动力学常数无差异，而细胞内的情况有待于进一步研究。
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aldose reductase
