kinase
n. [生化] 激酶；致活酶
n. (Kinase)人名；(日)木名濑 (姓)
n.
激酶，致活酶；
英英释义
kinase[ 'kaineiz, 'ki- ]
n.an enzyme that catalyzes the conversion of a proenzyme to an active enzyme
词组短语
protein kinase蛋白激酶
creatine kinase肌酸激酶
thymidine kinase胸苷激酶；胸腺嘧啶核苷漱酶
双语例句
用作名词(n.)
Sunitinb is a novel multitargeted receptor tyrosine kinase inhibitor.
苏尼替尼是一种新型的多靶点酪氨酸激酶抑制剂。
Electively targeting of signaling pathways using protein kinase inhibitors would have a potential advantage over receptor blockers.
这种用来选择性地阻断信号转导途径的蛋白激酶抑制剂可能是一种潜在的有利的受体阻断剂。
权威例句
The Phosphoinositide 3-Kinase PathwayThe protein kinase complement of the human genome.
The phosphatidylinositol 3-Kinase AKT pathway in human cancer.
The role of protein kinase C in cell surface signal transduction and tumour promotion.
mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt.
PYRAZOLE PYRAZINE AMINE COMPOUNDS AS KINASE INHIBITORS, COMPOSITIONS THEREOF AND METHODS OF TREATMENT THEREWITH
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia.
Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase.
Rosiglitazone counteracts palmitate-induced β-cell dysfunction by suppression of MAP kinase, inducible nitric oxide synthase and ca...
Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small ...
kinase (n.)
1902, from Greek kinein "to move" (see cite) + chemical suffix -ase.
1. The inhibitor of VEGF receptor tyrosine kinase was introduced in detail.
详细介绍了VEGF受体酪氨酸激酶抑制剂的研究进展。
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2. Response rates to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors in cancer treatment have been surprisingly and disappointingly low.
EGFR酪氨酸激酶抑制剂在肿瘤的治疗中的反应率是出乎意料和令人失望的低。
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3. The researchers gauged the severity of the attacks by measuring the levels of the enzymes creatine kinase and troponin-I, which are higher the more the heart muscle has been damaged.
研究人员通过测量酵素肌酸激酶和肌钙蛋白I的含量判定心脏病的严重程度，如果这些含量越高，就会有更多的心肌被破坏。
zuci.chaziwang.com
4. The crux of the experiment was to use two drugs in combination: an AKT (protein kinase B) inhibitor, and a BSO (buthionine sulfoximine), which reduces levels of glutathione.
实验的核心是两种药物联用：一种AKT（蛋白质激酶B）抑制剂，和一种BSO（丁硫氨酸亚砜胺），可以减少谷胱甘肽的水平。
www.indoomed.com
5. The kinetic property of glycerol kinase from debaryomyces sp.
甘油激酶基本动力学性质研究。
www.websaru.com
6. This may help to explain previous data indicating that inhibition of EGFR kinase activity is not sufficient to induce cell death, or to negate all of the functions of EGFR.
这可能解释以前的研究数据发现抑制酪氨酸激酶活性不足以诱导细胞死亡，或抑制EGFR的所有功能。
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7. Objective To assess the effect of tyrosine kinase inhibitor (2,5-MC) on the inhibition of in-stent inti-mal hyperplasia.
目的评估酪氨酸蛋白激酶抑制剂2，5-MC抑制支架植入术后内膜增殖的效果。
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8. Objective To evaluate the role of protein kinase C(PKC) in the thermal hyperalgesia evoked by local injection of endothelin-1(ET-1).
目的研究蛋白激酶C（PKC）途径在内皮素-1（ET-1）引起热痛觉过敏中的作用。
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9. Targeting both kinase-dependent and kinase-independent functions of EGFR may be necessary for more successful therapy in the future.
同时针对EGFR激酶依赖和激酶不依赖的功能可能是以后开展更成功的肿瘤治疗所必须的。
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10. ATP is formed in the payoff phase of glycolysis by two reactions, promoted by phosphoglycerate kinase and pyruvate kinase.
ATP在糖酵解的收获阶段经过两个反应生成，由磷酸甘油酸激酶和丙酮酸激酶催化。
dict.bigear.cn
11. Sunitinb is a novel multitargeted receptor tyrosine kinase inhibitor.
苏尼替尼是一种新型的多靶点酪氨酸激酶抑制剂。
dict.cn
12. Protein kinase assay was used to detect the activity of MKK6 in cells.
使用激酶活性测定法检测细胞内MKK6的激酶活性。
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13. Methods Serum cytosolic enzyme creatine kinase (CK) and its brain band isoenzyme (CK BB), lactate dehydrogenase (LDH) and aspartate aminotransferase (AST) were measured with autobiochemical analyzer.
方法采用全自动生化分析仪检测血清肌酸激酶（CK）、肌酸激酶脑型同工酶（CK-BB）、乳酸脱氢酶（LDH）以及天门冬氨酸氨基转换酶（AST）的含量。
zuci.chaziwang.com
14. Conclusion Genistein and daidzein were two effective inhibitors of recombinant human protein kinase CK2 in vitro.
结论染料木黄酮和大豆甙元是两种有效的重组人CK2全酶的抑制剂。
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15. Anti-cancer drugs that jam the enzyme, preventing its docking with the kinase, could halt cell over proliferation to treat such cancers.
干扰此酶的抗癌药物防止它与激酶对接，可以阻止细胞过度增殖，从而治疗这种癌症。
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16. Vandetanib inhibits the activity of tyrosine kinases, including those associated with epidermal growth factor receptor, vascular endothelial cell growth factor receptor, and protein tyrosine kinase 6.
凡德他尼抑制酪氨酸激酶的活动，包括那些与表皮生长因子受体，血管内皮细胞生长因子受体和酪氨酸蛋白激酶6相关。
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17. Adenosine monophosphate-activated protein kinase(AMPK) is considered to be an energy sensor, some energy metabolic hormones can cause changes of AMPK activity.
腺苷酸活化蛋白激酶被认为是机体的能量感受器，一些能量代谢激素可以引起其活性的变化。
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18. FLT3 Internal tandem duplication (ITD) and tyrosine kinase domain (TKD) mutations are seen in 30% of AML patients (pts) and are associated with poor survival.
30%的急性髓系白血病（AML）患者发生FLT3内部串联重复（ITD）和酪氨酸激酶域（TKD）突变，而且生存预后较差。
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19. Secondary FLT3-TKD mutations are associated with treatment failure with tyrosine kinase inhibitors.
继发性FLT3-TKD突变与酪氨酸激酶抑制剂治疗失败有关。
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20. The upstream kinase and biological significance of these phosphorylation events have yet to be elucidated (6).
此过程的上游激酶和这些位点磷酸化的生物学意义尚不明晰（6）。
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21. Binding of FLT3L to its cognate tyrosine kinase receptor, FLT3, activates STAT3 and STAT5 (1,3).
FLT3L结合到与它同源的酪氨酸激酶的受体FLT3结合激活STAT3和STAT5 （1，3）。
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22. Zhang Weihua and colleagues now shed some light on this issue by revealing a kinase-independent function of EGFR in maintaining cell survival.
最近，ZhangWeihua及期同事发现了EGFR独立于激酶之外维持细胞生存的功能，为深入理解这个问题带了一缕曙光。
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23. ATM kinase regulates a number of proteins involved in cell cycle checkpoint control, apoptosis, and DNA repair.
ATM激酶调节许多蛋白，涉及细胞周期检验点的控制、细胞凋亡和DNA修复。
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24. Kinase inhibitor.
激酶抑制剂。
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25. Objective:To investigate the roles of phosphatidylinositol 3-kinase(PI3K) in the regulation of expression of vascular endothelial growth factor(VEGF) in hepatocellular carcinoma(HCC) cells.
目的：研究磷脂酰肌醇3-激酶（PI3K）信号通路在肝癌细胞血管内皮生长因子（VEGF）表达调控中的作用。
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26. 5- and 2,6-disubstituted benzazole analogues useful as protein kinase inhibitors.
用作蛋白激酶抑制剂的2，5和2，6双取代的氮茚类似物。
dict.cn
27. Abstr: Objective To investigate the effect of protein kinase D inhibitor SD-208 on the proliferation, apoptosis and cell cycle of non-small cell lung cancer cells.
文章摘要：目的探讨蛋白激酶D抑制剂SD-208对非小细胞肺癌细胞增殖、凋亡及细胞周期的影响。
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28. In addition, while DNA damage has been found to inhibit PLK1 kinase activity, the Thr210Asp mutant is resistant to this inhibition (13).
另外，尽管DNA损伤被发现能够抑制PLK1激酶活性，苏氨酸（210位）被天冬氨酸取代后能够抵制这种抑制作用 （13）。
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29. Objective To observe the expression of protein kinase C(PKC)isoforms in pulmonary artery of chronic inflammatory pulmonary hypertension(PHT)rats.
目的研究慢性“炎症性”肺动脉高压大鼠在肺动脉高压形成过程中肺动脉蛋白激酶C（PKC）亚型的表达。
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30. Phosphorylation of Aurora A at Thr288 in its catalytic domain increases kinase activity.
极光激酶A催化结构域苏氨酸（288位）的磷酸化能够增强激酶的活性。
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31. PDGF受体酪氨酸激酶抑制剂在胰腺癌中是否有作用?
Is PDGF tyrosine kinase inhibitor effective in pancreatic cancer?
-- 来源 -- njtdyxyxb.nextage.cn
32. When wheat plants allowed to become deficient in potassium, pyruvate kinase activity increased.
当小麦植株令其缺钾时，丙酮酸激酶活性随之升高。
-- 来源 -- 英汉 - 辞典例句
33. butyrate kinase
丁酸激酶
-- 来源 -- 英汉 - 翻译参考[网络]
34. The name is soluble f-m-s-like tyrosine kinase one?
这种蛋白质叫做可溶解fms样酪氨酸激酶一，
-- 来源 -- 交互式慢速英语-秋季号 - Preeclampsia Study
35. glycerol kinase
甘油激酶
-- 来源 -- 英汉 - 翻译参考[网络]
36. adenylate kinase
腺苷酸激酶
-- 来源 -- 英汉 - 翻译参考[网络]
37. streptidine kinase
链霉胍激酶
-- 来源 -- 英汉 - 翻译参考[网络]
38. carbamate kinase
氨基甲酸激酶
-- 来源 -- 英汉 - 翻译参考[网络]
39. adenosine kinase
腺苷激酶
-- 来源 -- 英汉 - 翻译参考[网络]
40. homoserine kinase
高丝氨酸激酶
-- 来源 -- 英汉 - 翻译参考[网络]
kinase
