COMT
释义
[医][=catechol-O-methyltransferase]儿茶酚邻位甲基转移酶；
权威例句
COMT val158met genotype affects mu-opioid neurotransmitter responses to a pain stressor.COMT val158met Genotype Affects 碌-Opioid Neurotransmitter Responses to a Pain Stressor
Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia
A Highly Significant Association between a COMT Haplotype and Schizophrenia
A functional polymorphism in the COMT gene and performance on a test of prefrontal cognition.
Catechol-O-methyltransferase (COMT): biochemistry, molecular biology, pharmacology, and clinical efficacy of the new selective COMT ...
A Haplotype Implicated in Schizophrenia Susceptibility Is Associated with Reduced COMT Expression in Human Brain
Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in po...
Mannisto PT, Kaakkola S. Catechol-O-methyltransferase (COMT): biochemistry, molecular biology, pharmacology, and clinical efficacy o...
Breast cancer risk associated with genotype polymorphism of the estrogen-metabolizing genes CYP17, CYP1A1, and COMT: a multigenic st...
1. The German researchers took samples of cells from inside the mouths of 101 young men and women and tested them for a gene called COMT.
德国研究人员提取了101位年轻男性和女性嘴里的细胞样本，并且在样本中检测一种被称为COMT的基因。
article.yeeyan.org
2. Objectives To investigate whether Parkinson disease (PD) is associated with genetic polymorphisms of catechol O methyltransferase (COMT) gene caused by the point mutation of G1947→A in exon 4.
目的探讨儿茶酚胺氧位甲基转移酶（COMT）基因G1947→A位点突变所致的基因多态性与帕金森病（PD）遗传易患性的关系。
dict.cnki.net
3. Objective To study the expression of catecholamine metabolism related enzymes COMT and MAO in the lung tissues of a rat acute pulmonary embolism(PE) model.
目的探讨急性肺血栓栓塞大鼠的肺组织中儿茶酚胺代谢相关酶类氧甲基转移酶（COMT）和单胺氧化酶（MAO）的表达变化。
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4. Objective To investigate the association between catechol O-methyltransferase (COMT) gene and autism in Chinese children.
目的探讨儿童孤独症与儿茶酚氧位甲基转移酶（COMT）基因多态性的关系。
dict.cnki.net
5. The type of COMT gene did not affect how much the men and women won on the gambling game - but it did affect how much they gave to charity.
COMT基因的类型并不影响男性与女性在赌博游戏中能够赢多少——但是却会影响他们捐赠的多少。
sinaurl.cn
6. Conclusion The results suggested DRD2 gene and COMT gene may be associated with OCD in different onset ages.
结论DRD2基因和COMT基因可能与不同发病年龄的强迫症病因相关。
dict.cnki.net
7. Objective:Determine the association, if any, between COMT polymorphisms, preoperative anxiety and postoperative fentanyl dose.
目的：检验COMT基因多态性、术前焦虑及术后芬太尼镇痛剂量三者间是否存在相关。
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8. Objective To explore the relationship between dopamine D3 (DRD3), dopamine D2 (DRD2), catechol O methyltransferase (COMT) genes polymorphism and bipolar affective disorder.
目的探索多巴胺D3受体（DRD3）、多巴胺D2受体（DRD2 ）和儿茶酚氧位甲基转移酶（COMT）基因多态性与双相情感障碍的关系。
dict.cnki.net
9. Two alleles of the COMT gene as a result of a G/A transition in the exon 4 can lead to different COMT enzymatic activities.
COMT是儿茶酚-O-甲基转移酶的编码基因，其第4外显子的一个G/A转换可产生不同活性的等位基因。
dj.iciba.com
10. The job of the COMT gene is to get rid of stress hormones such as epinephrine.
COMT的作用就是消除肾上腺素之类的压力激素。
www.qqenglish.com
11. In this paper, the CYP1-and COMT-mediated metabolism of estradiol and their relationship with the risk of breast cancer were reviewed and the related anti-cancer drugs design was introduced.
综述雌二醇代谢中CYP1和COMT的作用及其与乳腺癌的关系，介绍相关的抗肿瘤药物的研发。
kns50.chkd.cnki.net
12. In this paper, the CYP1- and COMT-mediated metabolism of estradiol and their relationship with the risk of breast eaneer were reviewed and the related anti-cancer drugs design was introduced.
综述雌二醇代谢中CYP1和COMT的作用及其与乳腺癌的关系，介绍相关的抗肿瘤药物的研发。
lib.cqvip.com
13. Objective: To explore the association between anxiety disorder and polymorphism of catechol-O-methyltransferase(COMT).
目的探讨焦虑症与儿茶酚邻甲基转移酶基因多态性的相关性。
dict.cnki.net
14. Much genetic research has revealed that this COMT functional polymorphism was related to human psychiatric disorders.
许多遗传学研究报道，这种功能多态性与人类精神类疾病相关。
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15. Objective: To study the hypothesis whether polymorphism in estrogen-metabolizing gene, COMT, impact on the risk of benign prostatic hyperplasia among old men.
目的：研究参与雌激素代谢解毒的儿茶酚—O—甲基转移酶（COMT）基因多态性与老年男性良性前列腺增生的关系。
www.fabiao.net
16. The rates of COMT gene expression down-regulation in OCD patients with OCPD and ones without OCPD were 14%and 56%respectively.
伴强迫人格与无强迫人格的强迫症患者COMT基因表达水平分别下调14%和56%；
dx.doi.org
17. Methods The case control association study was used to analyze the association of polymorphism in the DRD3, DRD2, COMT genes with 105 patients of bipolar affective disorder and 128 controls.
方法使用病例对照的关联分析方法，对10 5名双相情感障碍患者和12 8名对照者之DRD3、DRD2和COMT的多态性进行检测，并进行关联分析。
dict.cnki.net
18. Methods The polymorphism of COMT gene was analyzed in 105 patients with PD and 115 healthy adult individuals with polymerase chain reaction restriction fragment length polymorphism (PCR RFLP).
方法利用聚合酶链反应限制性片段长度多态性（PCRRFLP）技术分析了10 5例帕金森病患者与115名正常健康成人对照组COMT的基因多态性位点频率。
dict.cnki.net
19. DRD2P and COMT genotyping were carried out using PCR followed by RFLP and statistical analysis of genotype frequencies between TS patients and healthy controls was performed using SPSS programme.
采用病例对照研究的方法，用聚合酶链反应（PCR）和限制性片段长度多态性分析（RFLP）研究TS患者与健康对照间DRD2P、COMT基因的基因型频率有无统计学差异。
www.fabiao.net
20. DRD2P and COMT genotyping were carried out using PCR followed by RFLP and statistical analysis of genotype frequencies between TS patients and healthy controls was performed using SPSS programme.
采用病例对照研究的方法，用聚合酶链反应（PCR）和限制性片段长度多态性分析（RFLP）研究TS患者与健康对照间DRD2P、COMT基因的基因型频率有无统计学差异。
www.fabiao.net
COMT
